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Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Dexamethasone speeds up hair loss in mice, while cyclosporin A slows it down.

IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.

Flutamide rarely causes liver toxicity in prostate cancer patients.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.

Foals with Rhodococcus equi infection often have other health problems that lower their chances of survival.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Using platelet-rich plasma with microneedling works better for acne scars than microneedling with water.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Nerves and chemicals in the body can affect hair growth and loss.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Steroids help hair regrowth, and minoxidil slows post-steroid hair loss, but effects are temporary.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.