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    Glossary Genome-Wide Association Study

    research method identifying genetic variants linked to specific traits

    A Genome-Wide Association Study (GWAS) is a research approach used to identify genetic variations linked to specific diseases or traits by scanning the genomes of many individuals. By comparing the DNA of people with and without a particular condition, researchers can pinpoint genetic markers that may contribute to the risk of developing that condition, providing insights into its biological mechanisms.

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    1. A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features Nature Communications · 2016 · 196 citations
    2. Genomewide Scan for Linkage Reveals Evidence of Several Susceptibility Loci for Alopecia Areata The American Journal of Human Genetics · 2007 · 143 citations
    3. Genome-wide association study in Japanese females identifies fifteen novel skin-related trait associations Scientific reports · 2018 · 58 citations
    4. Genetic determinants of skin ageing: a systematic review and meta-analysis of genome-wide association studies and candidate genes Journal of PHYSIOLOGICAL ANTHROPOLOGY · 2025 · 3 citations
    5. The Genetics of Seborrheic Dermatitis: A Candidate Gene Approach and Pilot Genome-Wide Association Study Journal of Investigative Dermatology · 2017 · 15 citations
    6. The Polycystic Ovary Syndrome Evolutionary Paradox: a Genome-Wide Association Studies–Based, in silico, Evolutionary Explanation The Journal of Clinical Endocrinology and Metabolism · 2014 · 47 citations
    7. Genome-wide association study in alopecia areata implicates both innate and adaptive immunity Nature · 2010 · 717 citations
    8. Genome-Wide Association Study for Udder Conformation Traits in Chinese Holstein Cattle Animals · 2022 · 10 citations
    9. Identification of Candidate Genes for Min Pig Villi Hair Traits by Genome-Wide Association of Copy Number Variation Veterinary sciences · 2023 · 3 citations
    10. Genome wide association analysis of root hair traits in rice reveals novel genomic regions controlling epidermal cell differentiation BMC plant biology · 2023 · 2 citations
    11. Genome-Wide Association Study of Alopecia Areata in Taiwan: The Conflict Between Individuals and Hair Follicles Clinical, cosmetic and investigational dermatology · 2023 · 1 citations
    12. Genome-Wide Association Study of Fiber Diameter in Alpacas Animals · 2023 · 1 citations
    13. Genome-wide association study reveals candidate genes associated with body weight and wool traits in Ordos fine-wool sheep Frontiers in Veterinary Science · 2026
    14. Genome-Wide Associations with Body and Fleece Weight in United States Sheep Genes · 2025
    15. Genome-wide Scan and Fine-Mapping Linkage Study of Androgenetic Alopecia Reveals a Locus on Chromosome 3q26 American Journal of Human Genetics · 2008 · 62 citations
    16. A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients Breast cancer research · 2013 · 32 citations
    17. Hirsutism Beyond PCOS: Genome-wide Evidence for Genetic Factors Journal of Investigative Dermatology · 2026
    18. Six Novel Susceptibility Loci for Early-Onset Androgenetic Alopecia and Their Unexpected Association with Common Diseases PLOS Genetics · 2012 · 87 citations
    19. Molecular Genetics of Alopecias Current problems in dermatology · 2015 · 9 citations
    20. Predicting Human Appearance from DNA for Forensic Investigations Security science and technology · 2016 · 5 citations
    21. Common Variants in the Trichohyalin Gene Are Associated with Straight Hair in Europeans American journal of human genetics · 2009 · 234 citations
    22. Four Independent Mutations in the Feline Fibroblast Growth Factor 5 Gene Determine the Long-Haired Phenotype in Domestic Cats Journal of Heredity · 2007 · 75 citations
    23. Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness Nature communications · 2017 · 64 citations
    24. Genetic Basis of Alopecia Areata Dermatologic clinics · 2012 · 40 citations
    25. The Genetic Architecture of Alopecia Areata Journal of Investigative Dermatology Symposium Proceedings · 2013 · 23 citations
    26. GWASs Identify Genetic Loci Associated with Human Scalp Hair Whorl Direction Journal of Investigative Dermatology · 2023 · 4 citations
    27. A Comprehensive Review of GWASs of Human Hair Traits Journal of Investigative Dermatology · 2025 · 1 citations
    28. Recent advances in the genetics of alopecia areata Medizinische Genetik · 2023
    29. Male-pattern hair loss: Comprehensive identification of the associated genes as a basis for understanding pathophysiology Medizinische Genetik · 2023
    30. The biology and genetics of curly hair Experimental Dermatology · 2017 · 65 citations