Search
for

    Did you mean Genomic Instability?
    Glossary Genomic Instability

    increased tendency of DNA to acquire mutations

    Genomic instability refers to an increased tendency of an organism's DNA to acquire mutations, which can lead to various genetic disorders, including cancer. For a layperson, it's like having a book where the words and sentences keep changing, making it hard to understand the original story. For professionals, it involves mechanisms such as DNA replication errors, defective DNA repair, and chromosomal rearrangements.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Safe Selection of Genetically Manipulated Human Primary Keratinocytes with Very High Growth Potential Using CD24 Molecular Therapy · 2007 · 25 citations
    2. IMPACT OF BIOMARKER IN PREDICATIVE TO RESPONSE ADJUVANT CHEMOTHERAPY AND OVERALL SURVIVAL IN FEMALES INFECTED WITH BREAST CANCER: A REVIEW ARTICLES MINAR International Journal of Applied Sciences and Technology · 2025
    3. The character “hairless” in the mouse Journal of Genetics · 1931 · 35 citations
    4. Deciphering principles of morphogenesis from temporal and spatial patterns on the integument Developmental Dynamics · 2015 · 19 citations
    5. Booby Trap: Cancer gene spurs production of DNA-assaulting chemicals that alert and defuse rescue molecule (Cancer; Oxidative damage) Science of aging knowledge environment · 2002
    6. Effects of Melatonin Supplementation on Hormonal, Inflammatory, Genetic, and Oxidative Stress Parameters in Women With Polycystic Ovary Syndrome Frontiers in Endocrinology · 2019 · 81 citations
    7. Comprehensive Genomic Profiling of Cutaneous Adnexal Carcinomas: A Genomic Landscape Study Dermatopathology · 2026
    8. The population dynamics of cancer: a Darwinian perspective International journal of epidemiology · 2006 · 64 citations
    9. Decision letter: Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma 2016
    10. Central hair loss in African American women: Incidence and potential risk factors Journal of The American Academy of Dermatology · 2010 · 76 citations
    11. Advances in Lipid Nanoparticle‐Based Disease Treatment ChemMedChem · 2025 · 13 citations
    12. Causal relationship between gut microbiota and androgenetic alopecia: A Mendelian randomization study Medicine · 2024
    13. Mutations in the vitamin D receptor and hereditary vitamin D-resistant rickets BoneKEy Reports · 2014 · 107 citations
    14. Prevalence and Predictors of Premature Graying of Hair Before the Age of 30: A Cross‐Sectional Study in Saudi Arabia Journal of Cosmetic Dermatology · 2024
    15. A Homozygous Frameshift Mutation in the<i>HOXC13</i>Gene Underlies Pure Hair and Nail Ectodermal Dysplasia in a Syrian Family Human Mutation · 2013 · 30 citations
    16. Blank Spots in the Map of Human Skin: The Challenge for Xenotransplantation International Journal of Molecular Sciences · 2023
    17. Decision letter: Structural basis of malodour precursor transport in the human axilla 2018
    18. Adult Stem Cells Circulation research · 2019 · 41 citations
    19. Studying SARS-CoV-2 infectivity and therapeutic responses with complex organoids Nature Cell Biology · 2021 · 36 citations
    20. Adrenal Cortex Tumors and Hyperplasias InTech eBooks · 2011 · 2 citations
    21. A General Paediatric Approach to Ankyloblepharon–Ectodermal Dysplasia–Cleft Lip/Palate Syndrome in Infancy: A Case Report Journal of Paediatrics and Child Health · 2025
    22. Schmallenberg virus infection suspected in a calf born to an imported heifer 2021
    23. Associaton of Insulin Resistance Linked Diseases and Hair Loss in Elderly Men. Finnish Population-based Study Central European Journal of Public Health · 2006 · 55 citations
    24. The long and the short of it: evidence that <i>FGF5</i> is a major determinant of canine ‘hair’‐itability Animal genetics · 2006 · 73 citations
    25. Generic Development of Topical Dermatologic Products: Formulation Development, Process Development, and Testing of Topical Dermatologic Products The AAPS Journal · 2012 · 188 citations
    26. The Genetics of Human Skin Disease Cold Spring Harbor Perspectives in Medicine · 2014 · 24 citations
    27. A Practitioner's Guide to Hair Loss Part 1—History, Biology, Genetics, Prevention, Conventional Treatments, and Herbals Alternative and Complementary Therapies · 2004 · 3 citations
    28. Polarized microscopy in genetic hair disorders: case series 2025
    29. What does acne genetics teach us about disease pathogenesis? British Journal of Dermatology · 2019 · 29 citations
    30. Genetic links between atopy, allergy, and alopecia areata: insights from a Mendelian randomization study Allergy Asthma and Clinical Immunology · 2024 · 11 citations