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Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.

Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

A gene deletion causes the "hairless" trait in Iffa Credo rats.

Light microscopy is useful for diagnosing different hair disorders.

Some diseases can improve the outcomes of other diseases, leading to new treatment possibilities.

The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.

A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.

New genes linked to ichthyosis were found, but there's still no cure; treatment options are improving.

Gray hair is caused by reduced melanin production or transfer issues, linked to aging and possibly health conditions, with treatments focusing on color camouflage.

Lipase H is important for hair follicle function and shaping hair fibers.

Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Discoid Lupus Erythematosus often causes scarring hair loss, is influenced by genetics and environment, and requires early treatment to prevent worsening.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.

A wearable device using electric stimulation can significantly improve hair growth.

Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Adrenal disorders can cause lasting brain and behavior issues in children.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Researchers found a new mutation causing total hair loss from birth.

New treatments for PCOS focus on managing symptoms and improving fertility.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.