research Proxalutamide Reduces the Rate of Hospitalization for COVID-19 Male Outpatients: A Randomized Double-Blinded Placebo-Controlled Trial
Proxalutamide significantly lowered hospital admissions for male COVID-19 patients compared to a placebo.
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research The Prolactin Receptor as a Therapeutic Target in Human Diseases: Exploring New Potential Indications
Blocking the prolactin receptor might help treat various diseases, but more research is needed.
research Systematic Review and Meta-Analysis of the Efficacy and Safety of Leflunomide and Methotrexate in the Treatment of Rheumatoid Arthritis
Leflunomide and methotrexate are equally effective for rheumatoid arthritis but have different side effects.
research Clinical Comparison of Extended-Release Divalproex Versus Delayed-Release Divalproex: Pooled Data Analyses From Nine Trials
Extended-release divalproex is better tolerated and more effective for seizures and psychiatric symptoms than delayed-release divalproex, but doesn't reduce hair loss.
research The Clinical Presentation of Systemic Lupus Erythematosus
Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.
research Phase II Evaluation of VDC-1101 in Canine Cutaneous T-Cell Lymphoma
VDC-1101 shows potential as a treatment for canine cutaneous T-cell lymphoma.
research Nutrition and the Deleterious Side Effects of Nutritional Supplements
Taking too many vitamin and mineral supplements can cause serious health problems.
research Phase I Safety and Pharmacokinetic Study of SU-014813 in Combination with Docetaxel in Patients with Advanced Solid Tumors
The drug combination was safe and showed promise in treating advanced tumors.
research Ovarian Surgery for Symptom Relief in Women with Polycystic Ovary Syndrome
Ovarian drilling surgery is not clearly better than medical treatments for PCOS symptoms.
research Principles of Chemotherapy
Chemotherapy is crucial for treating gynecological cancers but requires careful management due to severe side effects.
research Zinc: A Complementary Factor in the Treatment of Chronic Hepatitis C?
Zinc supplementation may help improve treatment outcomes for chronic hepatitis C.
research Liposomes in Cancer Therapy
Liposomes show promise in cancer treatment by delivering drugs with less toxicity and improved effectiveness.
research A Compartmental Model of Uranium in Human Hair for Protracted Ingestion of Natural Uranium in Drinking Water
The model helps predict uranium levels in human hair from drinking contaminated water, offering an alternative to urine tests.
research Topiramate vs Divalproex Sodium in the Preventive Treatment of Migraine: A Prospective Real-World Study
Both topiramate and divalproex sodium effectively reduce migraine frequency and are generally well-tolerated.
research An Unusual Case Report of Rapunzel Syndrome Trichobezoar in a 3-Year-Old Boy
A 3-year-old boy had a rare hairball condition usually seen in teenage girls.
research Spontaneous Improvement of Cronkhite-Canada Syndrome in a Postpartum Female
A young woman's Cronkhite-Canada syndrome improved on its own after she gave birth.
research Minoxidil Overdose With ECG Changes: Case Report and Review
Minoxidil overdose caused heart changes, treated with stomach wash, charcoal, and IV fluids.
research Alopecia Areata Treated With Hydroxychloroquine: A Retrospective Study of Nine Pediatric Cases
Hydroxychloroquine may help treat alopecia areata in children.
research Management of Cutaneous and Extracutaneous Side Effects of Smoothened Inhibitor Therapy for Advanced Basal Cell Carcinoma
The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.
research Cyclosporine With and Without Systemic Corticosteroids in Treatment of Alopecia Areata: A Systematic Review
Cyclosporine combined with corticosteroids is more effective for severe alopecia areata than cyclosporine alone.
research Therapeutic Efficacy and Safety of Kang-Ai Injection Combined with Platinum-Based Doublet Chemotherapy in Advanced NSCLC: A Meta-Analysis
Kang-ai injection with platinum-based chemotherapy improves tumor response and immune function while reducing side effects in advanced lung cancer.
research Tardily Accelerated Neurologic Deterioration in Two-Step Thallium Intoxication
Thallium poisoning can cause worsening nerve damage and vision loss without typical symptoms.
research Trichomegaly of the Eyelashes After Treatment with Erlotinib in Non-Small Cell Lung Cancer
A cancer patient's eyelashes grew excessively without other common side effects after taking the cancer drug erlotinib.
research Open-Label, Randomized, Multicenter, Phase III Study Comparing Oral Paclitaxel Plus Encequidar Versus Intravenous Paclitaxel in Patients With Metastatic Breast Cancer
Oral paclitaxel plus encequidar improved tumor response and caused less neuropathy but more serious infections than intravenous paclitaxel.
research Methotrexate Treatment of Generalized Granuloma Annulare: A Retrospective Case Series
Methotrexate improved skin condition in 64% of patients with generalized granuloma annulare.
research Gemcitabine in Combination with Vinorelbine in Elderly Patients with Anthracycline- and Taxane-Pretreated Metastatic Breast Cancer
The combination of gemcitabine and vinorelbine is effective and safe for treating elderly patients with advanced breast cancer previously treated with anthracyclines and taxanes.
research Natural Hair Supplement: Friend or Foe? Saw Palmetto, A Systematic Review in Alopecia
Saw palmetto supplements may modestly improve hair regrowth with few side effects, but more research is needed.
research Alopecia Areata Flare Patterns in Children and Young Adults on Systemic Tofacitinib
Tofacitinib can regrow hair in alopecia areata patients, but some may experience flares during treatment.
research A Synbiotic Preparation (SIM01) for Post-Acute Covid-19 Syndrome in Hong Kong (Recovery): A Randomised, Double-Blind, Placebo-Controlled Trial
SIM01 significantly reduced post-COVID symptoms and is safe.
research Anxiety in the Medically Ill: A Systematic Review of the Literature
Many patients with various medical conditions experience anxiety, which worsens their quality of life and raises healthcare costs.