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In this study, manipulation of the enzyme 5α-reductase type 2 in human hepatocytes altered lipogenesis, suggesting clinical implications for patients using 5α-reductase inhibitors by affecting glucocorticoid action on hepatic lipid metabolism.

This study found that STAT3 directly inhibited the activity of the sheep FST gene promoter, consequently reducing cell proliferation and promoting a better understanding of hair follicle development mechanisms.

This study highlights the global prevalence of hirsutism in women and reviews its diagnostic criteria, potential underlying causes like polycystic ovary syndrome, and treatment options, emphasizing the need for tailored, multifaceted management and acknowledging the distress it causes patients.

In this study, patients with polycystic ovary syndrome self-reported higher hirsutism scores compared to clinician assessments, but only clinician scores correlated with biochemical markers of hyperandrogenism.

The April 2014 issue of "Fertility and Sterility" discussed various reproductive health topics, including hormone therapy benefits, sperm and genetic factors in male infertility, and the link between PCOS and diabetes.

In this study, researchers used the FAERS database to identify rare adverse events potentially linked to spironolactone, finding new safety signals such as a possible association with male endometriosis, suggesting further research is needed to understand these findings better.

This study concluded that spironolactone may be an effective therapy for a subgroup of hirsute patients, as it reduced plasma testosterone and improved certain hair growth measures.

This study comprehensively compared different crystalline forms of finasteride, including the new finasteride DMF solvate hemihydrate, to better understand their structural characteristics and intermolecular interactions.

This abstract mentions a strategic task force by ISHRS to raise awareness about hair restoration but contains no specific research findings.

This study found that the 5α-steroid metabolite profile in men with inherited 5α-reductase deficiency is similar to those taking the drug finasteride, suggesting the gene affects multiple steroid substrates.

This study found that using a combined LH and FSH stimulation protocol significantly increased clinical pregnancy rates in women with low ovarian reserve compared to the standard protocol.

This study found that a human relevant potency threshold for estrogen receptor alpha agonism may serve as a health-protective screening tool, and highlights inference performance as essential for scientific confidence frameworks.

This study by Gao et al. reports that two nonsteroidal selective androgen receptor modulators, S1 and S4, demonstrated tissue-selective actions in rats, suppressing prostate growth while maintaining muscle growth without altering hormone levels.

Finasteride helped treat a 28-year-old's facial skin condition.

This review discusses female pattern hair loss, emphasizing its complex causes and the limited treatment options available, and reports no new clinical results.

This article reviews the etiology of FPHL, distinguishing between androgen-dependent and androgen-independent forms, but reports no new clinical findings; it highlights the need to better understand its pathogenesis.

This review discusses treatment options for hirsutism in women of childbearing age, focusing on the use of contraceptives, CPA, spironolactone, and third-line therapies, and reports no clinical results.

This study found that both combined therapy with goserelin and oral contraceptives, and oral contraceptives alone, significantly reduced hair diameter in severe hirsutism without a significant difference between treatments.

This study described the clinical and genetic features of two Iranian siblings with hereditary vitamin D resistant rickets, identifying a specific VDR gene mutation contributing to their symptoms.

This study found that nuclear androgen receptor levels varied among females with androgen-dependent dermatoses, being highest in hirsutism, which may suggest superior androgen stimulability compared to acne and androgenetic alopecia.

The document concludes that individualized Facial Feminization Surgery plans and comprehensive care are crucial for successful outcomes.

This article reviews the increasing incidence of frontal fibrosing alopecia since its first description in 1994 and reports no new results.

This study demonstrated that safflower seeds can be engineered to express oleosin-FGF10, which showed a dose-dependent effect on cellular proliferation, potentially facilitating scalable protein production.

This study found that stimulating the olfactory receptor OR2A4/7 with cyclohexyl salicylate promoted human hair growth and increased progeny of hair follicle epithelial stem cells in an ex vivo setting.

This study found that women with PCOS who had a higher serum estrone-to-estradiol ratio were more likely to exhibit higher fasting insulin and postprandial glucose levels, even after adjusting for BMI and waist-to-hip ratio.

This study found that various steroids affected the mRNA expression of enzymes involved in lipid metabolism in hamster flank organs, with different impacts depending on the steroid and combination used.

This report presents a case where female pattern hair loss might be linked to tamoxifen use, with increased androgen receptor expression observed in the affected scalp area.

This study found that FRβ knockout mice exhibited autoimmune symptoms and slower tumor growth compared to wild type mice, suggesting that the FRβ receptor may play a role in regulating immune responses in tumors and autoimmune conditions.

This study found that ethanol extract of Tubtim Chumphae rice bran downregulates SRD5A gene expression, similarly to finasteride, suggesting potential use as an anti-hair loss product.