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New treatments are making advanced prostate cancer management more complex but also more hopeful.

The document concludes that better training and education are needed for proper cancer screening and criticizes the GMC's inaction as harmful to clinical ethics in the UK.

The book is a detailed guide on hair growth issues and treatments, recommended for specialists and hospital libraries.

Alopecia areata often starts around age 23, can be permanent in 30% of cases, and treatments are usually temporary.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Manage vitiligo with treatments, address emotions, and use camouflage techniques.

Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.

Stem cell niches support, regulate, and coordinate stem cell functions.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Different hair evaluation methods have their own pros and cons, and using multiple methods together is best for accurate hair loss diagnosis and tracking.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

The VVG stain effectively differentiates scar tissue from normal skin and helps classify types of permanent alopecia.

After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

Finding eosinophils near hair bulbs helps diagnose alopecia areata.

Other common signs, not just the well-known immune cells around hair bulbs, are important for diagnosing hair loss from alopecia areata.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

Older age, higher BMI, and family history of diabetes increase the risk of gestational diabetes in pregnant women.

Niosomes improve minoxidil skin penetration for hair loss treatment.

Macrophages are essential for successful skin growth in reconstructive surgery.

Minoxidil's effectiveness decreases as vehicle evaporates; concentration and thermodynamic activity matter.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.