The human scalp has different types of pigment cells in hair follicles with varying abilities to produce pigment.
January 2020 in “Journal of Genetics and Gene Therapy” The combination of hair follicle stem cells and PRP shows promise for treating hair loss in Asian men and women.
401 citations,
January 2013 in “Postepy Dermatologii I Alergologii” The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.
57 citations,
April 2009 in “Differentiation” SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
41 citations,
April 2019 in “PLOS genetics” CD34+ and CD34- melanocyte stem cells have different regenerative abilities.
9 citations,
January 2013 in “Journal of Cutaneous and Aesthetic Surgery” Transplanting body hair helped repigment and treat a man's vitiligo.
1 citations,
January 2011 in “International Journal of Trichology” Hair follicle stem cells have significant potential for treating various disorders.
September 2016 in “Journal of dermatological science” Adult skin cells can be used to create new hair in a lab.
7 citations,
February 2019 in “International Journal of Dermatology” Gray hair is caused by reduced melanin production or transfer issues, linked to aging and possibly health conditions, with treatments focusing on color camouflage.
2 citations,
May 2018 in “Australasian Journal of Dermatology” Some patients' hair grew back black and white after chemotherapy.
1 citations,
September 2016 in “Springer eBooks” Sebum production varies by individual and is influenced by age, gender, and hormones, affecting skin and hair health.
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Advancements in hair biology include new treatments and tools for hair growth and alopecia.
The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
46 citations,
May 1986 in “Seminars in Reproductive Medicine” Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.
40 citations,
December 2011 in “British Journal of Dermatology” Women's hair generally gets thinner and less dense starting in their mid-thirties, with hair loss becoming more common as they age due to both genetics and environment.
33 citations,
September 2012 in “Australasian Journal of Dermatology” Chemotherapy can cause hair changes similar to alopecia areata, which might lead to misdiagnosis.
27 citations,
January 2002 in “Exogenous Dermatology” Chronic exposure to sunlight may worsen male pattern baldness and protecting the scalp from the sun could slow it down.
25 citations,
March 2012 in “Journal of oncology pharmacy practice” An 81-year-old man's white hair began to regain its original color while he was treated with lenalidomide, suggesting that graying hair might be reversible.
21 citations,
December 2016 in “PLOS ONE” Scientists made skin stem cells from other human cells with over 97% efficiency, which could help treat skin conditions.
19 citations,
May 1992 in “International Journal of Dermatology” Some alternative vitiligo treatments show promise, but none are as effective as psoralens and UVA.
13 citations,
October 2002 in “Journal of Investigative Dermatology” The upper half of a human hair follicle can grow a new hair in a mouse, but success is rare.
12 citations,
January 2010 in “Hair transplant forum international” The survival rates of hair grafts are similar regardless of how they are trimmed.
11 citations,
July 2017 in “Expert Opinion on Investigational Drugs” New hair loss treatments may include topical medications, injections, and improved transplant methods.
9 citations,
November 2017 in “Journal of Glaucoma” Latanoprost eye drops may cause skin depigmentation.
8 citations,
January 2017 in “Stem Cells International” A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.
8 citations,
January 2003 in “Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy” Chemotherapy may cause recurring hair loss due to an autoimmune response.
6 citations,
January 2007 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Gray hair regained color after thyroid hormone treatment.
4 citations,
May 2012 in “Tissue Engineering and Regenerative Medicine” Scientists created three types of structures to help regrow hair follicles, and all showed promising results for hair regeneration.
2 citations,
January 2017 in “Journal of Pigmentary Disorders” Genetics, stress, and health issues can cause early hair greying, which affects self-esteem, and there's no cure, only hair dye.
June 2023 in “Medeniyet medical journal” People with alopecia areata have similar retinal structures but thicker choroidal regions compared to those without the condition.