4 citations
,
September 2010 in “Journal of Dermatological Science” This article reviews keratosis follicularis squamosa, a keratinizing disorder predominantly found in the Japanese population, but reports no new clinical results.
1 citations
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November 2024 in “Pharmaceutical Sciences” This review study found that vesicular carriers like liposomes, niosomes, invasomes, and transferosomes can enhance drug penetration through follicles, benefiting treatments for alopecia, acne, and infections, as well as potentially facilitating systemic delivery of antihypertensive drugs and insulin.
February 2026 in “Frontiers in Medicine” This review discusses strategies to identify, prevent, and manage complications in FUE and reports no new clinical results.
July 2025 in “Dermatology Practical & Conceptual” Topical eyedrops may cause eyelash whitening and skin lightening around the eyes.
January 2018 in “Elsevier eBooks” The document concludes that proper diagnosis and treatment of follicular disorders are crucial, with specific treatments for conditions like acne, drug-induced eruptions, and rosacea.
26 citations
,
March 2014 in “International journal of pharmaceutics” This study confirmed that the novel solid lipid microparticle formulation of adapalene demonstrated follicular penetration potential and targeted particle erosion in sebum in in vitro tests.
18 citations
,
May 2016 in “Aesthetic Surgery Journal” This study found that body hair transplantation using follicular unit extraction was effective and resulted in high satisfaction among selected patients with limited scalp donor hair.
9 citations
,
May 2020 in “Journal of Cosmetic Dermatology” This review discusses various follicular unit excision methods, punch designs, and motorized devices, highlighting their roles in reducing hair follicle transection rates and optimizing graft harvesting for individual patient characteristics.
4 citations
,
January 2005 in “Elsevier eBooks” This article discusses the key considerations and techniques necessary for successful Follicular Unit Transplantation in hair restoration surgery and reports no new clinical results.
July 2026 in “Clinical Cosmetic and Investigational Dermatology” In this study, a liposomal-encapsulated Sesbania grandiflora formulation significantly improved hair and scalp health in adults with hair loss over 180 days, showing enhanced hair density, thickness, growth rate, and tensile strength compared to placebo, with no related adverse events reported.
47 citations
,
November 2012 in “Pharmaceutical research” This study found that surface modified nanoparticles showed increased skin permeation and improvement in allergic contact dermatitis, independent of the follicular pathway.
32 citations
,
November 2004 in “Journal of pharmaceutical sciences” This study quantifies the follicular uptake of tea tree oil in bovine udder skin, with microemulsion showing the highest concentration among different formulations tested.
40 citations
,
January 2018 in “Pharmaceutics” This study found that nanoemulsions incorporating skin penetration enhancers significantly increased the permeation of minoxidil through human skin compared to aqueous control solutions.
37 citations
,
October 2009 in “Dermatology” This study suggests that the action of minoxidil in stimulating hair growth likely occurs at the follicular dermal papilla, though it does not induce new follicle formation.
25 citations
,
February 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, topical application of the SCD1 inhibitor XEN103 significantly reduced sebaceous gland size and number in mouse skin, suggesting potential local therapeutic effects for acne treatment without systemic side effects.
January 2025 in “Expert Opinion on Drug Delivery” This study discusses the limitations of current FDA-approved treatments for androgenic alopecia, noting significant sexual side effects with oral finasteride and formulation challenges with topical minoxidil, and highlights the potential of nanocarriers to improve drug delivery to hair follicles.
December 2025 in “Cureus” This study reports a case of traumatic anserine folliculosis in a young male, where treatment with topical retinoids and keratolytics combined with avoiding friction significantly improved symptoms after nine months.
77 citations
,
January 2015 in “International Journal of Biological Macromolecules” This study developed minoxidil sulphate-loaded chitosan nanoparticles that doubled drug delivery to hair follicles in vitro compared to a control solution, suggesting potential for improved alopecia treatment.
33 citations
,
October 2016 in “European Journal of Pharmaceutical Sciences” This study found that a novel effervescent formulation significantly increased minoxidil sulphate accumulation in hair follicles and skin compared to a standard minoxidil solution.
19 citations
,
July 1993 in “Journal of Applied Toxicology” This study found that various petroleum distillates caused significant skin changes in mice, with severity varying based on the product and penetration pathway, potentially leading to skin tumors through non-genotoxic mechanisms in longer-term exposure.
15 citations
,
February 2014 in “Toxicology Letters” This study found that osthole, a coumarin derivative, demonstrated significantly higher skin accumulation and potential skin irritation compared to coumarin, which showed negligible alterations in protein biomarkers.
13 citations
,
December 2017 in “Journal of Cosmetic and Laser Therapy” This study evaluated the use of low-level laser therapy for treating androgenic alopecia in adults, finding it a promising and safe at-home option for stimulating hair growth compared to sham devices, though further research is needed to confirm its clinical effectiveness.
13 citations
,
January 2016 in “Journal of the Egyptian Women's Dermatologic Society (Print)” This abstract discusses platelet-rich plasma therapy for patterned hair loss but provides no new clinical results, suggesting further research is needed to determine its effectiveness.
7 citations
,
November 1987 in “Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy” This article reviews the potential of topical minoxidil to cosmetically thicken hair in some individuals with male pattern hair loss, but it reports no new clinical results.
June 2026 in “International Journal of Drug Delivery Technology” In this review, researchers discussed various novel drug delivery systems, including lipid nanocarriers and polymeric nanoparticles, that may enhance treatment for alopecia by improving drug localization in hair follicles and reducing systemic exposure, potentially offering better outcomes than conventional treatments.
September 2025 in “Sahel Journal of Life Sciences FUDMA” This study reported that albino Wistar rats exposed to chemical hair straighteners showed significant hair fiber damage and scalp skin deterioration, which worsened with repeated and prolonged application, highlighting the cytotoxic potential of these products and potential systemic risks.
September 2025 in “Institutional Repositories DataBase (IRDB)” The nanoemulsion system effectively delivers drugs through the skin and shows promise for treating skin conditions.
April 2025 in “International Journal for Research in Applied Science and Engineering Technology” This study developed and tested a herbal hair growth tonic using medicinal plant extracts on animal models, reporting higher anagen/telogen ratio, follicular density, and hair length compared to controls, suggesting it as a potential natural alternative to synthetic products.
July 2022 in “SKIN The Journal of Cutaneous Medicine” This case report presents the first successful treatment of acne keloidalis nuchae with a combination of halobetasol 0.01% and tazarotene 0.045% lotion.
April 2021 in “Advances in Cosmetic Surgery” Hair restoration can be achieved through non-surgical treatments like minoxidil, antiandrogens, phototherapy, and PRP procedures, or through surgical methods like hair transplantation. Continued treatment is needed to maintain results, and full results are visible after 12-18 months.