50 citations
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May 2000 in “Fertility and Sterility” This study found that flutamide was more effective than finasteride in reducing hair growth in women with hirsutism over a one-year period.
1 citations
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February 2022 in “Brain Research Bulletin” This study found that finasteride reduced impulsivity in a rat model of pramipexole-induced probability discounting, possibly by normalizing D3 receptor expression in the nucleus accumbens.
August 2018 in “Journal of The American Academy of Dermatology” Finasteride, a hair loss drug, is linked to increased suicidal thoughts, particularly when used for hair loss.
June 2024 in “Drug and therapeutics bulletin” Finasteride can cause depression, suicidal thoughts, and lasting psychiatric and sexual issues.
11 citations
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August 2019 in “BMJ” This article reviews ongoing concerns about the safety of 5α-reductase inhibitors like finasteride, highlighting the lack of long-term data on persistent depression and sexual side effects after drug discontinuation; no new clinical results are reported.
November 2010 in “International Journal of Developmental Neuroscience”
This report describes a case of significant hair loss in a 51-year-old woman treated with paroxetine, which improved after stopping the medication, highlighting the complex nature of drug-associated alopecia.
September 2023 in “Journal of Cosmetic Dermatology” In this study, both finasteride and hydroxychloroquine were found to be equally effective, safe, and well-tolerated first-line treatments for frontal fibrosing alopecia in female patients, with no significant differences in efficacy between the two therapies over six months.
May 2026 in “Reactions Weekly” Finasteride and dutasteride may increase the risk of suicide and sexual dysfunction.
December 2025 in “Journal of Cosmetic Dermatology” This study found that finasteride use is not significantly associated with an increased risk of depression or suicide, based on Mendelian randomization analysis and COX regression analysis in a large UK Biobank cohort.
June 2021 in “Reactions Weekly” Finasteride caused serious side effects and led to six suicides.
September 2004 in “Inpharma Weekly” January 2011 in “Reactions Weekly”
February 2026 in “PubMed” In this study, adult male rats exhibited significant anxiety-like behaviors following finasteride withdrawal, including pronounced hyperactivity and novelty avoidance, highlighting potential parallels with post-finasteride syndrome observed in clinical settings.
7 citations
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November 2014 in “Clinical Therapeutics” This study observed that coadministration of finasteride and tamsulosin in healthy Chinese males appears unlikely to result in a clinically significant pharmacokinetic interaction.
January 2016 in “Reactions Weekly” No clear link found between finasteride and suicidal thoughts or actions.
1 citations
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January 2002 in “European Urology Supplements” Tamsulosin works faster, but both drugs have similar effects after 6 months.
33 citations
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October 1994 in “The Journal of Clinical Endocrinology and Metabolism” This study found that finasteride treatment significantly reduced hirsutism scores in women with idiopathic hirsutism over 6 months and was well tolerated.
October 2007 in “Nature Clinical Practice Urology” January 2017 in “The American Pharmacists Association eBooks” January 2017 in “The American Pharmacists Association eBooks” 42 citations
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August 2012 in “Psychoneuroendocrinology” Finasteride reduces certain behaviors caused by D1-like receptor agonists but not by D2-like receptor agonists in mice.
88 citations
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October 2002 in “Journal of Dermatology” In this study, 19 patients treated with finasteride for androgenetic alopecia developed moderate to severe depression, which resolved after stopping the medication, suggesting an association between finasteride and mood disturbances.
This trial explores whether spironolactone is more effective than cyclines for treating moderate acne in adult women, providing a potential alternative amidst concerns over antibiotic resistance.
August 2025 in “Psychiatry and Clinical Neurosciences Reports” This case report describes a woman who developed trichotillomania during long COVID and saw improvement in symptoms with the SSRI escitalopram.
17 citations
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October 1994 in “The Journal of Clinical Endocrinology and Metabolism” This study found that finasteride may effectively reduce hirsutism in women with idiopathic hirsutism, as evidenced by lower Ferriman-Gallwey scores and hormone levels, without significant adverse effects.
April 2022 in “Reactions Weekly”
6 citations
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December 2008 in “Clinics in Dermatology” This study presents four cases of delusions of parasitosis and introduces escitalopram as a potential therapy, highlighting its fewer side effects compared to the commonly used pimozide.
May 2024 in “Reactions weekly”
April 2018 in “Journal of Investigative Dermatology” This study suggests that weekly oral finasteride may be a promising alternative to isotretinoin for treating nodulocystic acne, showing substantial improvements with lower incidence of sexual dysfunction.