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The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Taking 5-α reductase inhibitors for prostate enlargement or hair loss does not significantly raise the risk of erectile dysfunction.

Diagnosing hair loss disorders needs clinical, dermoscopic, and histological differences, and checking menstrual cycle, weight changes, drug therapy, and nail changes.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

Hair-thread Tourniquet Syndrome, where hair or thread tightly wraps around a body part, is not rare and requires early detection to prevent serious damage.

Adults with certain skin conditions may have higher levels of inflammation in their body.

Diagnosing PCOS in teenagers should focus on signs of excess male hormones and not rely solely on ovarian ultrasound or irregular periods, and should be reassessed in adulthood.

Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.

A new storage solution may increase hair transplant graft survival.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Hair dyes can change hair color temporarily or permanently but may cause side effects like skin reactions and hair damage.

Flutamide, dutasteride, and finasteride dissolve differently in supercritical carbon dioxide, with dutasteride dissolving the least.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Over 67 genes linked to ichthyosis help improve diagnosis and treatment.

Finasteride improved symptoms in a schizophrenia patient.

5α-Reductase inhibitors can negatively affect male sexual function and, in some cases, significantly reduce sperm count, but these effects may be reversible.

Finasteride may not stop severe hair loss after stopping minoxidil.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

Carbamazepine may cause reversible nail detachment.

Combining skin tissue pathology with genetics has greatly improved the diagnosis and understanding of certain skin diseases.

PRP improves hair thickness for both genders, but only increases hair density in men.

Finasteride use may increase the risk of male breast cancer.

Dr. Vera H. Price's 1979 work emphasizes the importance of accurate diagnosis and personalized treatment for hair loss.

Etanercept improved symptoms of a specific type of psoriatic arthritis in a patient who didn't respond to other treatments.

A woman with acromegaly experienced severe hair loss from a drug called Lanreotide Autogel, which improved after stopping the treatment.

A man with KID syndrome developed a rare cancer in a long-term skin infection.

Finasteride interacts with terazosin, but not doxazosin; caution needed.

The Edwardian medical campaign linked maternal drinking to infant mortality and national decline, influencing hygiene education and leading to a ban on children under 14 from pubs.

Finger length ratio may indicate male hair loss.

Some skin patients have body image issues linked to social difficulties but want psychological help.