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Scientists found gene mutations that affect hair loss, skin stem cells, and skin disorders, and identified drugs that may help treat blood vessel and skin conditions.
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research Induction of Secreted WNT Factor WISP1/CCN4 by Human Prostate Stromal Cells Under Microenvironmental Hypoxia
Human prostate cells produce more WISP1/CCN4 when there's not enough oxygen.
research The Role of Local and Systemic Leptin in Androgenetic Alopecia
Higher leptin levels link to hair loss.
research A Polymorphism in the Matrix Metalloproteinase-1 Gene Promoter Is Associated with the Presence of Polycystic Ovary Syndrome in Caucasian Women
A specific gene variation is linked to a higher risk of polycystic ovary syndrome in Caucasian women.
research Divergent Molecular Signatures of Regeneration and Fibrosis During Wound Repair
Disrupting YAP signaling in skin cells leads to scar-free healing directed by specific cell signals.
research Integrated Single-Cell RNA-Sequencing Data of Unwounded and Wounded Mouse Skin and Fibroblasts
The dataset includes detailed genetic information from mouse skin cells before and after injury.
research Integrated Single-Cell RNA-Sequencing Data of Unwounded and Wounded Mouse Skin and Fibroblasts
The dataset includes detailed genetic information from mouse skin cells before and after injury.
research Neutrophil Extracellular Traps Impair Regeneration
Neutrophil extracellular traps slow down hair follicle healing after injury.
research Hair Transplantation into the Nape of the Neck
Hair transplant surgery can successfully treat hair loss at the back of the neck.
research Treatment of Pseudofolliculitis With a Pulsed Infrared Laser
Pulsed infrared laser can effectively reduce symptoms of pseudofolliculitis barbae.
research Epithelial–Mesenchymal Transition in Keloid Tissues and TGF-β1–Induced Hair Follicle Outer Root Sheath Keratinocytes
Keloid scars may form due to changes in skin cell characteristics and specific protein signaling.
research Repeal And Replace: Adipocyte Regeneration In Wound Repair
Skin wounds can create fat cells that help regenerate hair follicles, with BMP signaling playing a crucial role in this process.
research Tissue and Circulating MicroRNA Co-expression Analysis Shows Potential Involvement of miRNAs in the Pathobiology of Frontal Fibrosing Alopecia
Certain microRNAs might help identify and understand Frontal Fibrosing Alopecia.
research Extensive Donor Site Keloids in Follicular Unit Extraction Hair Transplantation
Hair transplant can cause hard-to-treat keloids in some patients.
research From Hair to Liver: Emerging Application of Hair Follicle Mesenchymal Stem Cell Transplantation Reverses Liver Cirrhosis by Blocking the TGF-β/Smad Signaling Pathway to Inhibit Pathological HSC Activation
Hair follicle stem cell transplants can reverse liver cirrhosis by blocking harmful cell activation.
research Dihydroartemisinin Attenuates Benign Prostatic Hyperplasia in Rats by Inhibiting Prostatic Epithelial Cell Proliferation
Dihydroartemisinin helps reduce prostate enlargement in rats by stopping the growth of prostate cells.
research A Simple Technique to Distinguish Fibrosing Alopecia in a Pattern Distribution from Androgenetic Alopecia and Concomitant Seborrheic Dermatitis
A simple scalp scraping can effectively distinguish fibrosing alopecia from androgenetic alopecia with seborrheic dermatitis.
research Topical Spironolactone in the Treatment of Evaporative Dry Eye Disease
Spironolactone may help improve symptoms and tear quality in dry eye disease.
research High Fat Diet and the Adipocyte to Myofibroblast Transition: Implications for Systemic Sclerosis Cutaneous Fibrosis
A high fat lard diet may protect against skin fibrosis and affect hair growth.
research Trichoscopy – A Valuable Tool for Identifying Conditions Mimicking Androgenetic Alopecia
Trichoscopy helps tell apart other hair loss conditions from common hair loss.
research Lichen Planopilaris: Mechanisms, Subtypes, and Diagnosis
Lichen planopilaris causes permanent hair loss and scarring due to damage to hair follicles and can be mistaken for other hair loss conditions.
research Multimodal Molecular Analysis Reveals Divergent Trajectories of Wound Regeneration Versus Fibrosis
Verteporfin treatment in mice led to complete skin healing without scarring.
research LB965 Follicular Trochanters: A Potential Mechanism for Stem Cell Depletion in Scarring Alopecia
Hair follicle bumps with stem cells might contribute to permanent hair loss by getting disconnected due to scarring.
research Dermatopathology Quiz: Which Alopecia Does the Patient Have?
The patient has frontal fibrosing alopecia (FFA).
research Autologous Stromal Vascular Fraction Cells Combined with Platelet-Rich Plasma for Androgenic Alopecia Treatment: A Case Series
The treatment led to denser, thicker hair growth and less hair loss.
research Faculty Opinions Recommendation of Inhibition of Beta-Catenin Signaling in Dermal Fibroblasts Enhances Hair Follicle Regeneration During Wound Healing
research Ezetimibe Reduces Enlarged Prostate in an Animal Model of Benign Prostatic Hyperplasia
Ezetimibe effectively reduces prostate size in cases of benign prostatic hyperplasia.
research Clinical Recognition and Management of Alopecia in Women of Color
The document concludes that it's important to recognize and treat hair loss in women of color, considering their unique hair characteristics and psychological impact.
research Common Causes of Pediatric Alopecia
Hair loss in children is often caused by scalp infections, immune disorders, hair pulling, stress, and requires careful treatment due to emotional effects.
research Trichoscopic Findings in Androgenetic Alopecia
Trichoscopy, a hair loss evaluation technique, found that people with Androgenetic Alopecia have more thin hairs, yellow dots, and perifollicular discoloration than healthy individuals.