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Spironolactone effectively treats female acne with few side effects.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Transgender patients in critical care need better-trained medical staff and specific guidelines.

Sex hormones' effects on COVID-19 are unclear and more research is needed to understand their potential as treatment.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.

Many children and teens referred to gender services receive hormone treatments, but more research is needed on their long-term care and outcomes.

Dermatologists are essential in helping transgender and gender diverse patients with skin and hair issues related to gender affirmation and hormone therapy.

The document concludes that respectful, gender-affirming healthcare improves mental health and encourages continued medical care for transgender and non-binary individuals.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

Heat and chemicals improve finasteride delivery to scalp and hair follicles, potentially enhancing treatment for hair loss.

The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.

Eflornithine's effectiveness for women with facial hirsutism is unclear.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.

The document concludes that treatments for female hair loss and excessive hair growth are temporary and not well-studied.

The document concludes that management strategies for PCOS are important due to its common occurrence and associated health risks.

Women with congenital adrenal hyperplasia (CAH) have more sexual function issues than those with polycystic ovary syndrome (PCOS), but physical activity can improve sexual functioning in all women.

Uterine transplants for transgender women are feasible but need more research.

Air Vice-Marshal Sir Ralph Jackson significantly advanced dialysis technology in the UK.

Addressing underrepresentation in Parkinson's research is crucial for better treatments and understanding.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Cyproterone acetate is a safe treatment that causes mild feminizing effects and is more effective with added estrogens.

Cyproterone acetate is a safe treatment that causes mild feminizing effects in adolescent trans-girls.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.

Finasteride and minoxidil together promote hair growth better than either alone.

Honokiol might help reduce male skin aging by maintaining testosterone levels.