June 2023 in “Plastic and Reconstructive Surgery – Global Open” This review found that exosome use in aesthetic plastic surgery shows promise in areas like skin rejuvenation and hair restoration, with laboratory studies indicating enhanced outcomes, but clinical evidence remains largely anecdotal, and no exosome-based products have FDA approval.
April 2022 in “Medicina estética” This review of female androgenetic alopecia treatments reports limited therapeutic options due to unclear pathogenesis, with minoxidil as the only FDA-approved treatment and adjuvant therapies under investigation.
25 citations
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March 2018 in “Journal of oncology practice” This study found that scalp cooling effectively reduces chemotherapy-induced hair loss, especially with taxane-based regimens, and recent U.S. trials support its safety, despite logistical and insurance challenges.
9 citations
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February 2018 in “Journal of Patient-Reported Outcomes” This study developed two comprehensive patient-reported outcome measures for systemic lupus erythematosus to assess symptom fluctuations and impacts, following FDA guidelines, which may aid in clinical studies and practice.
6 citations
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May 2023 in “Drugs” This study reports that baricitinib was more effective than placebo in promoting hair growth in adults with severe alopecia areata after 36 weeks of treatment in clinical trials.
3 citations
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April 2011 in “Expert Review of Dermatology” This review discusses the use of mesotherapy, highlighting its popularity and the lack of large, randomized controlled trials, and advises cautious use.
2 citations
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March 2025 in “Lynchburg Journal of Medical Science” This literature review highlights varying recommendations for testosterone use in peri- and postmenopausal women, noting its accepted role in treating hypoactive sexual desire disorder but stressing controversy and lack of FDA-approved options for broader use.
2 citations
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October 2020 in “Journal of Pharmacy And Bioallied Sciences” This study reviewed existing literature on chloroquine and hydroxychloroquine's safety and efficacy in COVID-19 management, finding mixed clinical evidence and highlighting the need for more rigorous trials to determine their potential role in treatment.
2 citations
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April 2019 in “Journal of the American Society of Nephrology” This study found that fluconazole increased water transport in renal cells via effects on aquaporin-2 channels, suggesting potential as a treatment for nephrogenic diabetes insipidus, though clinical trials are needed to confirm efficacy in humans.
1 citations
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December 2024 in “Indian Dermatology Online Journal” This research notes that biologics and small molecules are effective for treating nail psoriasis and alopecia areata, albeit with precautions for adverse events, but no clinical trials have been published for their use in treating nail lichen planus and atopic dermatitis.
1 citations
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June 2004 in “Sexuality, reproduction & menopause” This review discusses the use of eflornithine cream for managing hirsutism in women and reports promising results from clinical experience but presents no new clinical trials.
October 2025 in “Indian Journal of Dermatology” This study explored recent advancements in hair restoration, particularly focusing on plant-derived exosomes and biomimetic polypeptides, which enhance hair follicle regeneration and growth, offering a promising alternative to human or animal-derived exosomes subject to FDA restrictions.
April 2024 in “Lasers in medical science” This study reviews the use of lasers and light therapies as treatment options for managing the two most common types of alopecia—androegenetic alopecia and alopecia areata—highlighting that existing FDA-approved drugs like minoxidil and finasteride are partially effective, necessitating additional therapeutic approaches.
August 2023 in “Journal of Dermatological Treatment” This systematic review concluded that mesotherapy shows potential for improving hair growth outcomes, yet lacks standardized regimens and requires further large-scale trials to establish its efficacy and safe use.
This comprehensive review analyzes androgenetic alopecia treatments, discussing the mechanisms, costs, efficacy, and safety of FDA-approved drugs like minoxidil and finasteride, as well as newer non-FDA-approved options that have shown effectiveness across various studies.
August 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identifies diltiazem as a promising repurposed drug for treating influenza, supported by its antiviral activity and gene modulation effects, leading to a Phase II clinical trial authorization.
February 2023 in “European Journal of Medical Research” This study identified several drugs that may be potential candidates for repurposing as anti-hyperhidrosis treatments, based on their association with hypohidrosis or anhidrosis in the FDA Adverse Event Reporting System.
November 2013 in “Journal of clinical & experimental dermatology research” This narrative review discusses the potential of urinary bladder matrix as a bio-scaffold in hair restoration but provides no new clinical results or trials; it highlights regenerative technology and suggests further exploration.
4 citations
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January 2020 in “PubMed” This source reports that JAK inhibitors, such as ruxolitinib, baricitinib, and tofacitinib, have led to hair regrowth in alopecia areata patients and animal models, but their long-term safety and effectiveness remain uncertain, with ongoing trials to further investigate these factors.
1 citations
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January 2017 in “Springer eBooks” This review discusses recent advances in understanding alopecia areata's disease mechanisms and highlights JAK molecules as promising therapeutic targets, but reports no new clinical results; controlled trials are needed.
39 citations
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September 2015 in “Clinical Therapeutics” This review summarizes updated US prescribing information for teriflunomide in relapsing multiple sclerosis, highlighting its efficacy in reducing lesion activity and relapse rates but noting potential adverse effects such as headache and diarrhea.
7 citations
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April 2012 in “Clinical investigation” This review examines existing research on transdermal testosterone for treating hypoactive sexual desire disorder, suggesting it improves female sexual function with minimal side effects but highlights the need for more long-term safety data.
1 citations
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October 2022 in “Molecular therapy” This study found that betibeglogene autotemcel significantly improved transfusion independence in 89% of patients with transfusion-dependent beta-thalassemia, although the high cost and manufacturing challenges may limit widespread adoption.
May 2024 in “Psychiatric News” In this study, analysis of electronic health records suggested that patients taking semaglutide were significantly less likely to experience suicidal ideation compared to those on non-GLP-1 obesity or diabetes medications.
3 citations
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October 2011 in “QJM” This study found that 5α-reductase inhibitors significantly reduced low-grade prostate cancer incidence in men but nearly doubled the incidence of high-grade prostate cancers.
December 2025 in “JMU Scholoraly Commons (James Madison University)” This study found that combining platelet-rich plasma with topical 5% minoxidil increased hair density and patient satisfaction more than minoxidil alone in treating androgenetic alopecia.
11 citations
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June 2005 in “Journal of Cosmetic Dermatology” Lasers in hair transplantation show promise but are not yet standard, with current methods causing some side effects and needles still being preferred for creating recipient sites.
1 citations
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January 2023 in “Cutis” This article highlights disparities in the prevalence of alopecia areata among people with skin of color and suggests this information could help dermatologic providers address challenges in treating this population.
May 2011 in “Psychiatric News” This article provides regulatory updates, legal briefs, and industry news, reporting no new clinical findings.
August 2010 in “Oncology Times” This article discusses the approval and perceived potential of Provenge, a new prostate cancer vaccine, highlighting its capability to extend survival in certain patients while also noting ongoing debates about its cost and mechanisms; it reports no new clinical results.