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A 13-year-old boy with Cushing syndrome has high cortisol levels from a pituitary gland issue and underdeveloped sexual characteristics.

Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.

Children with classic congenital adrenal hyperplasia have thicker heart fat and are at higher risk for heart problems and early atherosclerosis.

Children with classic congenital adrenal hyperplasia have thicker heart fat and more heart and blood vessel risk factors, especially if their condition is not well-controlled.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

PCOS patients have more central body fat, which can be effectively measured using DEXA.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.

A new MBTPS2 gene variant disrupts fat metabolism and collagen production, causing Osteogenesis imperfecta.

Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Tiny fat-derived particles can help repair soft tissues by changing immune cell types.

About 6.5% of young Caucasian women in Spain have polycystic ovary syndrome.

Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.

Overweight women with PCOS have higher levels of certain hormones that could indicate a higher risk of heart and metabolic problems.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

Black ethnicity, prior PSA tests, enlarged prostate, and family history increase prostate cancer risk; Asian ethnicity, obesity, smoking, diabetes, and less sexual activity or no children decrease risk.

Women with PCOS have higher levels of a certain growth factor, which can be reduced by taking metformin.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

Women with PCOS have lower ghrelin levels and a weaker response to sugar, which might affect their feeling of fullness and lead to overeating.

Mice with CBS deficiency are healthier on a low-methionine diet.

Methionine restriction works better than betaine for treating CBS deficiency symptoms in mice.

Changing the diet of mice lacking the enzyme CBS can affect symptoms related to the genetic condition.