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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Too much androgen can cause hair loss; finasteride may help.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Manatee whiskers are specially adapted for touch in water.

The conclusion is that fat grafting is safe and effective but carries risks that need careful management.

The pseudo 'fringe sign' can also appear in frontal fibrosing alopecia, not just in traction alopecia, showing that this condition may be more common than thought.

Two patients with porphyria cutanea tarda experienced their grey hair turning dark again.

Eyebrow loss has many causes and requires accurate diagnosis for proper treatment.

WNT10A mutations cause varied symptoms in patients with odonto-onycho-dermal dysplasia.

The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.

Intense exercise at night can delay the body's internal clock gene expression by 2 to 4 hours.

Taking L-tryptophan supplements might cause a condition similar to scleroderma in some people, which can get better after stopping the supplement and starting corticosteroid therapy.

Sodium Valproate nanospanlastics could be a safe and effective treatment for Androgenic Alopecia, with fewer side effects than minoxidil.

A young woman's Cronkhite-Canada syndrome improved on its own after she gave birth.

Treating excessive hair in women requires a holistic approach, including medical, aesthetic, and emotional support.

Birth control pills can help reduce mild to moderate acne in women.

The spironolactone cream did not reduce hair growth in women with hirsutism.

Tamoxifen caused hair loss in a 52-year-old woman.

The cause of alopecia areata was unknown, and while various treatments existed, no best treatment was agreed upon.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

A woman with a rare adrenal tumor and hormonal disorder had improved testosterone levels after surgery, but her menstrual irregularities continued.

A Korean woman with complete hair loss regrew her hair after taking tofacitinib, with no side effects.

Skin health and diseases are closely linked to metabolic processes.

Acne is caused by increased sebum, abnormal skin shedding, bacteria, and inflammation, not dirt; treatments vary from creams to antibiotics or isotretinoin, with severe cases needing a dermatologist's care.

The document concludes that early diagnosis and treatment are crucial for managing skin diseases in ferrets.