40 citations
,
August 2018 in “Skin appendage disorders” This review examines complementary and alternative medicine for alopecia and finds limited support from robust clinical trials, highlighting the need for standardized studies to evaluate efficacy and safety.
3 citations
,
April 2011 in “Expert Review of Dermatology” This review discusses the use of mesotherapy, highlighting its popularity and the lack of large, randomized controlled trials, and advises cautious use.
343 citations
,
December 2008 in “Endocrine Reviews” This review discusses the various evidence-based and potential applications of metformin in treating and preventing symptoms and complications associated with polycystic ovary syndrome but reports no new clinical results.
198 citations
,
October 2011 in “Journal der Deutschen Dermatologischen Gesellschaft” This article discusses the development of an evidence-based guideline for treating androgenetic alopecia and reports no new research results.
145 citations
,
November 2017 in “Journal of The European Academy of Dermatology and Venereology” This guideline review by the European Dermatology Forum evaluates current treatments for androgenetic alopecia but reports no new research findings, aiming to assist dermatologists in selecting safe and effective therapies.
April 2025 in “International Journal of Homoeopathic Sciences” In this study, individualized homoeopathic treatment with Natrum muriaticum resulted in a significant improvement in a 16-year-old girl with alopecia areata, showcasing a notable outcome at the Govt. Homoeopathic Medical College in Trivandrum.
42 citations
,
July 2015 in “Journal of The American Academy of Dermatology” This review discusses diagnostic and treatment considerations for women with cutaneous hyperandrogenism, noting therapeutic options are more effective for hirsutism and acne than for androgenetic alopecia, but reports no new clinical results.
April 2026 in “International Journal of Homoeopathic Sciences” This case report observed that a 23-year-old male with androgenic alopecia experienced significant improvement, including complete resolution of baldness, after nine months of treatment with the homeopathic medicine Lycopodium clavatum 200.
January 2024 in “International Journal of Homoeopathic Sciences” In this case study, an 18-year-old girl with patchy alopecia areata and associated symptoms, such as scalp itching and dandruff, showed improvement after 4 months of treatment with homeopathic medicine.
11 citations
,
February 2007 in “Journal of Child and Adolescent Psychiatric Nursing” This review discusses the challenges of diagnosing and treating pediatric bipolar disorder and highlights the potential benefits of combined psychopharmacological treatments, noting no long-term efficacy from mood stabilizer monotherapy.
April 2024 in “Dermatology and therapy” This study surveyed dermatologists in Greece and Italy and found significant variability and challenges in the diagnosis and treatment of alopecia areata, including limited use of severity scores and diverse treatment approaches, particularly for special site involvement and chronic cases.
January 2026 in “Clinical Cosmetic and Investigational Dermatology” This expert opinion article presents insights from dermatologists and aesthetic physicians on using polynucleotides (Rejuran®) for skin hydration, rejuvenation, structural support, barrier repair, and scar remodeling, noting their favorable safety profile but highlighting the need for more robust evidence and research.
151 citations
,
May 2014 in “American Journal of Clinical Dermatology” This review concluded that oral finasteride for men and topical minoxidil for both genders have the most evidence supporting their effectiveness and safety for treating androgenetic alopecia.
72 citations
,
July 2014 in “American journal of clinical dermatology” This review analyzed randomized controlled trials on alopecia areata treatment and found that while several treatments showed effectiveness, most studies had limitations affecting their interpretability.
38 citations
,
January 2001 in “Neuroepidemiology” This paper discusses the limitations of clinical trials in evaluating combination treatment regimens for Alzheimer's disease and ischemic stroke, highlighting the extensive resources required for such trials.
36 citations
,
December 2016 in “Journal of The American Academy of Dermatology” In this study, researchers evaluated the hair pull test and found that normal values should be reduced to two hairs or fewer, with no significant impact from hair washing, brushing, or lifestyle factors such as hair texture and medication use.
8 citations
,
October 2022 in “Dermatology practical & conceptual” This source reports that tofacitinib and ruxolitinib showed potential efficacy and acceptable safety profiles in treating various autoimmune disorders, including alopecia areata and psoriasis, based on a review of clinical studies, while recommending physicians consider the individual risks and benefits.
February 2026 in “Frontiers in Medicine” This review discusses strategies to identify, prevent, and manage complications in FUE and reports no new clinical results.
60 citations
,
December 2015 in “Lasers in Medical Science” This review concluded that FDA-cleared low-level laser therapy devices are safe and effective for patients with male and female pattern hair loss who do not respond to or tolerate standard treatments.
April 2016 in “Journal of The American Academy of Dermatology” This study suggests that while low-cost USB microscopes can correctly identify certain hair shaft features, their ability to detect other crucial trichoscopic features is limited, indicating they are not reliable for routine scalp assessments without further trials.
2 citations
,
March 2016 in “The Journal of Dermatology” The researchers reported that the facial Psoriasis Log-based Area and Severity Index (fPLASI) more reliably and sensitively captured clinical improvement in facial psoriasis than the existing facial Psoriasis Area and Severity Index (fPASI).
In this case report, the authors detail a successful management of early scalp ischemia after hair transplantation using the FLOW protocol, which emphasizes cause correction, local vasodilation, oxygenation optimization, and wound care, resulting in recovery without necrosis.
March 2026 in “International Journal of Homoeopathic Sciences” This study reported a case where individualized homeopathic treatment notably reduced hair fall and promoted hair regrowth over nine months in a 40-year-old man with androgenic alopecia, while also improving his confidence and body image.
56 citations
,
March 2016 in “International Wound Journal” This review concludes that autologous split-thickness skin grafting remains the gold standard for safety and efficacy in treating chronic leg ulcers, with greater success in venous ulcers.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study evaluated current treatments for pediatric alopecia areata and found that high potency topical steroids had the strongest supporting evidence, with promising results also observed for anthralin ointment and other treatments in lower-grade studies.
30 citations
,
September 2016 in “BMJ” This study found that 5-α reductase inhibitors do not significantly increase the risk of erectile dysfunction in men with benign prostatic hyperplasia or alopecia, although duration of benign prostatic hyperplasia may elevate risk.
June 2026 in “International Journal on Science and Technology” This source redefines anti-aging medicine as "precision healthspan pharmacology," suggesting that rather than just treating diseases or accepting aging, pharmacology should focus on expanding functional capacity across various health domains, while emphasizing the importance of fundamental physiological and psychosocial health factors.
April 2026 in “Dermatology and Therapy” This study evaluated baricitinib 4 mg treatment in severe to very severe alopecia areata, reporting significant scalp hair regrowth by Week 52, especially in short-duration episodes, suggesting treatment should continue for at least a year before assessing failure.
This review suggests that combining Platelet-Rich Plasma and microneedling may enhance hair restoration outcomes in patients with androgenetic alopecia compared to using either therapy alone.
August 2013 in “Actas Dermo-Sifiliográficas” This study found that 29.1% of Cochrane Skin Group reviews provided strong evidence for or against interventions, showing their potential impact on clinical decision-making.