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Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Menopause causes dry skin, wrinkles, and hair changes, with hormone therapy helping but not recommended just for these issues.

Hormone therapy for breast cancer often leads to sexual issues like vaginal dryness and decreased libido.

Endocrine therapies for cancer significantly increase the risk of hair loss.

Eating a balanced diet with specific nutrients can help manage menopause symptoms and prevent related health issues.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.

A breast cancer patient had lasting hair loss after chemotherapy, which improved with minoxidil treatment.

The document concludes that individualized treatment and lifestyle changes are important for managing menopause symptoms and health risks.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.