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Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.

Menopause causes dry skin, wrinkles, and hair changes, with hormone therapy helping but not recommended just for these issues.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

The 2024 guideline updates recommendations for genetic testing, imaging, and sperm retrieval in male infertility.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

Hormone therapy for breast cancer often leads to sexual issues like vaginal dryness and decreased libido.

Age affects how certain proteins involved in COVID-19 infection are expressed in mice, but sex hormones and heart injury do not.

Certain drugs can worsen hair loss in people prone to androgenetic alopecia.

Centratherum anthelminticum seed extract effectively treats Polycystic Ovary Syndrome in rats.

Eating a balanced diet with specific nutrients can help manage menopause symptoms and prevent related health issues.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Endocrine therapies for cancer significantly increase the risk of hair loss.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

Some breast cancer treatments, like taxanes, can cause long-term hair loss.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.

The document concludes that individualized treatment and lifestyle changes are important for managing menopause symptoms and health risks.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

A breast cancer patient had lasting hair loss after chemotherapy, which improved with minoxidil treatment.