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The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Gender-affirming hormone treatments need better patient-focused outcome measurements and standardized data collection.

The document concludes that early and personalized treatment for PCOS in adolescents is crucial to manage symptoms and prevent long-term health issues.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Uterine transplants for transgender women are feasible but need more research.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

The conclusion is that there is a high demand for new contraceptives that provide both pregnancy prevention and protection against STIs, along with additional health benefits.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.

Oral contraceptives help treat hyperandrogenic disorders, improving symptoms like excessive hair and acne.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Menopause often leads to lower sexual desire and discomfort during sex, but treatment should be personalized and only if it bothers the woman.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Menopause affects hair and skin; more research needed for treatment.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

Quercetin may help improve symptoms of polycystic ovary syndrome.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Dutasteride treatment in men with mild to moderate COVID-19 reduced viral shedding, inflammation, and recovery time without serious side effects.

The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.

Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.