This study found that the enzyme encoded by Dgat1 acts as a retinol acyltransferase in murine epidermis, protecting against retinoid toxicity and alopecia by preventing retinol accumulation.
January 2002 in “Chinese Journal of Pharmaceuticals” This study reports the preparation of a key intermediate for finasteride and epristeride with a 69% overall yield from pregnenolone acetate.
83 citations
,
May 1999 in “International Journal of Dermatology” Hair loss that spreads out can often fix itself or be treated by finding and handling the cause.
67 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This review discusses telogen effluvium, a common type of hair loss, focusing on differentiation from other conditions and potential causes, but presents no new research findings.
40 citations
,
August 2018 in “Disease Models & Mechanisms” This review discusses cellular plasticity in skin and intestine, hypothesizing that mature cell reprogramming might contribute to tumorigenesis, and reports no new clinical results.
36 citations
,
October 2015 in “Cell reports” In this study, researchers found that Gab1 is critical in controlling the hair cycle and the self-renewal of hair follicle stem cells in mice.
28 citations
,
October 1987 in “PubMed” This study found that treating Tradescantia stamen hair cells with LiCl disrupts mitotic progression, leading to metaphase arrest, which can be reversed by myo-inositol or CaCl2 addition.
27 citations
,
April 2020 in “Molecular Biology and Evolution” This study found that ancient and modern Chinese goats share close genetic ties, originating from the Fertile Crescent, with genetic divergence influenced by China's climatic divisions.
27 citations
,
January 2012 in “Current Topics in Microbiology and Immunology” This study found similarities in the regeneration processes of MRL mouse ears and axolotl limbs, involving G2 cell cycle arrest and nerve-dependent mitosis, but the role of p21 in axolotl limb regeneration remains uncertain.
23 citations
,
September 2011 in “Journal of Dermatological Science” This study explored the effects of a new narrow-band red LED light on hair growth in mice, showing potential benefits compared to existing laser therapies.
23 citations
,
April 1991 in “Journal of The American Academy of Dermatology” Minoxidil solution can cause skin irritation and allergies in some users.
19 citations
,
October 2016 in “Nutrition in clinical practice” This article provides guidelines by ASPEN for managing parenteral nutrition shortages but reports no new clinical findings.
16 citations
,
August 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that MED1 plays a role in maintaining keratinocyte quiescence and hair follicle stem cell populations, as its absence in mice led to increased keratinocyte proliferation and reduced stem cell numbers.
13 citations
,
August 2007 in “Journal of Investigative Dermatology” Mouse hair can regrow in a special lab setup without serum.
13 citations
,
November 1973 in “Archives of Dermatology” This report describes a case where severe hair loss occurred as an early manifestation of Hodgkin disease, with the literature suggesting it might result from follicle destruction or toxic effects.
11 citations
,
January 1957 in “Journal of Histochemistry & Cytochemistry” This study demonstrated radiocalcium uptake in skin, eye, cartilage, and mucous glands, with the highest concentration in the hair follicle's keratogenous zone.
10 citations
,
December 2001 in “PubMed” This research suggests that both proposed pathways into hair fibers for molecule penetration are valid and complementary, with all fiber structures acting as potential routes for delivering materials.
9 citations
,
October 2025 in “MedComm” This review discusses the development and clinical progression of PROTAC technology for targeted protein degradation, highlighting its potential to address previously "undruggable" targets but reports no new clinical results.
2 citations
,
June 2020 in “Research Square (Research Square)” This study demonstrated that the antiandrogen drug enzalutamide may reduce TMPRSS2 levels in human lung cells and mouse lungs, supporting its potential as a COVID-19 treatment option.
2 citations
,
February 2016 in “Journal of sol-gel science and technology” This study found that 3-aminopropyltriethoxysilane penetrates hair fibers and improves the mechanical resistance of dry hair, addressing the needs for increased body in fine hair.
2 citations
,
August 2002 in “Zeitschrift für Hautkrankheiten” This review discusses the concept of telogen effluvium and emphasizes that its diagnosis requires detailed clinical evaluation and tests to identify underlying causes; no new clinical results are reported.
2 citations
,
July 1996 in “Annals of Internal Medicine” This letter argues that the association between fluconazole therapy and alopecia may be misattributed, suggesting instead that systemic fungal infections themselves could lead to hair loss.
1 citations
,
October 2013 in “A & A case reports” In this case report, a patient experienced hair loss after a surgical procedure but did not encounter the same issue following a later surgery with similar anesthesia.
July 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” This study observed distinct sex differences in hair growth cycles and regeneration in C3H/He mice, noting that females regenerated hair faster after adhesive material application, whereas males were more reliant on macrophage activity for this process.
January 2026 in “Dermatologic Therapy” This study found that a shampoo containing 1% selenium sulfide and 1% salicylic acid significantly improved the clinical signs and symptoms of seborrheic dermatitis and dandruff over an 8-week period.
This case report describes a 61-year-old woman with telogen effluvium, highlighting her concerns about exacerbated hair loss after surgery and aims to explore anesthesia techniques that might reduce hair shedding in such patients.
March 2025 in “Molecular Medicine” This study on C57BL/6 mice found that subcutaneous cholesterol injections significantly promoted hair regeneration by enhancing hair follicle stem cell proliferation, highlighting the role of the PKA-tyrosine hydroxylase-sympathetic nervous system pathway in this process.
November 2024 in “Comparative Biochemistry and Physiology Part D Genomics and Proteomics” In this study, epithelial cell-derived exosomes promoted fibroblast migration and inhibited their proliferation, suggesting a role in dermal condensate formation and hair follicle morphogenesis in cashmere goats.
August 2024 in “Advanced Healthcare Materials” In this study, water-soluble recombinant keratins, specifically RK81, were developed and used in microneedles to investigate their effect on hair growth, discovering that more than 40% of the hair follicles responded, demonstrating the potential for hair growth promotion.
March 2024 in “Bioactive Materials” This study found that modifying adipose-derived stem cells to overexpress the adhesion protein JAM-A increased the adhesion and resilience of dermal papilla cells in the context of androgenic alopecia, potentially facilitating hair regrowth despite challenges such as damage from dihydrotestosterone and macrophages.