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120-150 / 1000+ resultsresearch Engineered TGF-β-Enriched Exosomes Delivered by Dissolving Microneedles for Androgenetic Alopecia Therapy
research Electric Hair Follicular Stimulation
This article reviews the phases of hair growth and differences between androgenetic alopecia and telogen effluvium but provides no new clinical findings on Electric Follicle Stimulation.
research Dietary supplementation with Essential-oils-cobalt for improving growth performance, meat quality and skin cell capacity of goats
In this study, the authors reported that feeding cashmere goats with essential oil-cobalt significantly enhanced their growth, meat quality, and fiber quality, while stimulating immune-related physiological changes.
research Skin Transcriptome Analysis Identifies the Key Genes Underlying Fur Development in Chinese Tan Sheep in the Birth and Er-mao Periods
This study found that the FOS gene may play a significant role in promoting hair follicle development in Tan sheep, with elevated expression during the Er-mao period.
research Dumhetens rum i bildningens mitt
This study demonstrates that the CRISPR-Cas9 system can be used to successfully edit genes in large mammals, such as Cashmere goats, creating a valuable model for research on EDAR gene-related phenotypes.
research Study on the Activity of Sheep High-sulfur Keratin Promoter
This study found that the sheep high-sulfur keratin promoter B2C initiated GFP expression in sheep fibroblasts but remained inactive in mouse embryos.
research A Pilot Randomized Controlled Trial (RCT) Evaluating the Efficacy of an Exosome-Containing Plant Extract Formulation for Treating Male Alopecia
This study found that an exosome formulation with plant extracts significantly increased hair regrowth in men with male pattern alopecia compared to a placebo, without notable adverse effects.
research Inhibition of 5α-Reductase, IL-6 Secretion, and Oxidation Process of Equisetum debile Roxb. ex Vaucher Extract as Functional Food and Nutraceuticals Ingredients
This study observed that the ethyl acetate extract of Equisetum debile showed high activity against 5α-reductase and lipid peroxidation with no cytotoxicity on dermal papilla cells.
research A Novel Model System to Identify Cellular and Molecular Defects Underlying Rare Genetic Disorders
This study developed an in vitro model using NTERT keratinocytes expressing AEC-related TP63 mutations, which replicated skin defects observed in AEC patients and offers a valuable tool for understanding the disorder and developing new treatments.
research 17β-Estradiol Increases APE1/Ref-1 Secretion in Vascular Endothelial Cells and Ovariectomized Mice: Involvement of Calcium-Dependent Exosome Pathway
This study found that 17β-estradiol was the most powerful hormone for inducing APE1/Ref-1 secretion in cultured vascular endothelial cells, with secretion occurring through exosomes dependent on estrogen receptors and intracellular calcium.
research Interaction between stem cell factor and endothelin-1: effects on melanogenesis in human skin xenografts
In this study, the combination of SCF and ET-1 was found to significantly enhance skin pigmentation and melanin content in human skin xenografts on SCID mice compared to either treatment alone.
research Comprehensive analysis of microbiome and transcriptome revealed the mechanisms of Flammulina velutipes stem‐base enhance intestinal health in Gymnocypris eckloni
In this study, feeding Gymnocypris eckloni with Flammulina velutipes residues enhanced foregut morphology and beneficially altered gut microbiota, highlighting potential improvements in intestinal health for aquaculture use.
research Differences in Human Skin Between the Epidermal Growth Factor Receptor Distribution Detected by EGF Binding and Monoclonal Antibody Recognition
research A COMPARISON STUDY OF HAIR TONIC AND GEL FORMULATION OF ANGIOPTERIS EVECTA AS A HAIR GROWTH STIMULANT
This study evaluated hair tonic and gel formulations containing Angiopteris evecta root water extract and found both fulfilled pharmaceutical preparation standards, with the 12.5% hair tonic and 10.0% gel concentrations most effective for hair growth without a significant difference in performance.
research 102 EZH2 is required for human hair follicle growth and epidermal differentiation
In this ex vivo study, inhibiting Ezh2 with a small molecule slowed human hair growth by decreasing proliferation and increasing apoptosis in the outer root sheath.
research Effects of IGF-I and EGF on in vitro growth of hair follicles of sheep
This study found that treating sheep hair follicles with IGFⅠ and EGF stimulated growth, with EGF also accelerating cell differentiation and altering the growth cycle.
research Fine mapping of the human AR/EDA2R locus in androgenetic alopecia
This abstract contains only supplementary material information and reports no new research findings.
research GREEN TEA EXTRACT IN AN EYELASH GROWTH ENHANCER GEL FORMULATION: STABILITY TEST, EYE IRRITATION TEST, AND HUMAN EYELASH GROWTH ACTIVITY
This study found that a green tea extract gel was stable across various temperatures, did not cause eye irritation, and significantly increased eyelash growth compared to a placebo after two months of use in human volunteers.
research 257 Is EBF1 a negative regulator of WNT10A in the development of androgenetic alopecia?
This study found that in AGA, the risk allele at locus 2q35 alters WNT10A expression through EBF1, suggesting a potential androgen-dependent regulatory mechanism.
research Disproportionality analysis comparing safety profiles of sonidegib and vismodegib based on the FAERS database
This study reports that hedgehog pathway inhibitors, sonidegib and vismodegib, showed distinct adverse event patterns in real-world data, suggesting the need for further research to confirm these findings.
research Exosomes Derived from Fisetin-Treated Keratinocytes Mediate Hair Growth Promotion
In this study, fisetin applied to the dorsal skin of mice activated hair follicle stem cells through exosome secretion from keratinocytes, promoting hair growth.
research Effect of Eurycoma longifolia Extract on Testosterone Synthesis in TM3 Leydig Cells under Oxidative Stress
In this study, ELE was found to protect against oxidative stress-induced testosterone reduction in TM3 Leydig cells by increasing testosterone synthesis and decreasing its conversion.
research PERBANDINGAN ARMS-PCR DAN ALLELE-SPECIFIC PCR DALAM OPTIMASI GENOTIPING SNP rs1998076
This study concluded that allele-specific PCR (AS-PCR) is more reliable than tetra-primer ARMS-PCR for genotyping the SNP rs1998076 due to better stability and interpretability.
research PC-SPES Studies Promising, But Manufacturer Shuts Down
This study presented at the ASCO Annual Meeting reported that the epidermal growth factor receptor antibody ABX-EGF showed preliminary efficacy in renal cell cancer patients, with tolerable side effects, while bortezomib demonstrated clinical benefit in a significant proportion of multiple myeloma patients.
research 706 Engrailed-1 promotes eccrine sweat gland development in permissive environments
This study found that increasing En1 expression in mouse epidermis can convert cutaneous appendages to eccrine sweat glands, suggesting a role for En1 in eccrine gland development.
research A novel EDA variant that causes X-linked hypohidrotic ectodermal dysplasia in a Chinese family
In this study, prenatal ultrasonography was found to be a valuable tool for screening ectodermal dysplasia during pregnancy, and a new EDA gene variant associated with X-linked hypohidrotic ectodermal dysplasia was identified, aiding in more accurate diagnoses and reproductive decision-making.
research A woman with iatrogenic androgenetic alopecia responding to finasteride
EF and PXE not closely related.
research Nutritional Niche Construction and Local Adaptation: The Aquatic Resource-Driven Hypothesis of EDAR V370A in East Asia
This study presents a hypothesis that the EDAR V370A allele was positively selected in East Asian populations due to the stable aquatic resources in Late Pleistocene northern China, which may have offset the allele's metabolic costs and provided a selective advantage.
research Formulation and evaluation of self-nanoemulsifying drug delivery system for improved oral delivery of exemestane hydrochloride
This study explored the development of a self nanoemulsifying drug delivery system to enhance the solubility and oral bioavailability of exemestane HCl for breast cancer therapy.