This abstract does not provide any research findings or results; it is a website cookie policy and terms of use statement.
June 1997 in “The American Journal of Cosmetic Surgery” This article discusses the use of scalp stretching techniques to enhance donor hair supply for hair restoration, but it reports no new clinical findings.
February 2020 in “Bulletin of Experimental Biology and Medicine” Finasteride and GIZh-72 reduce inflammation, with GIZh-72 being more effective.
June 2019 in “Brain Imaging and Behavior” In this study, androgenic alopecia was identified as an independent predictor of abnormal white matter hyperintensities in the brain, suggesting it may serve as a surrogate marker for cerebral small vessel disease linked to arteriolosclerosis.
April 2017 in “Journal of Investigative Dermatology” This study found that human iPSC-derived dermal papilla precursor cells can regenerate hair follicle structures, offering a potential new treatment approach for permanent alopecia.
September 1997 in “Journal of The European Academy of Dermatology and Venereology” New treatment improves male hair loss.
108 citations
,
September 2002 in “The Journal of clinical investigation/The journal of clinical investigation” This study found that reducing testosterone levels in male mice accelerates wound healing and decreases inflammation, suggesting a potential therapeutic target for improving wound repair in elderly males.
12 citations
,
November 2020 in “Journal of Dermatological Science” In this study, miR-324-3p was found to promote differentiation and migration in cultured keratinocytes and is highlighted as a potential target for treating androgenic alopecia.
1514 citations
,
December 2011 in “Fertility and sterility” This consensus report reviews current knowledge and identifies knowledge gaps concerning the various health aspects of polycystic ovary syndrome, without presenting new clinical findings.
855 citations
,
June 2009 in “The Journal of Clinical Endocrinology & Metabolism” The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.
688 citations
,
June 2007 in “Cell Stem Cell” This study found that deleting the ATR gene in adult mice led to rapid onset of age-related traits such as hair graying and osteoporosis through reduced regenerative capacity.
658 citations
,
June 2003 in “Endocrine reviews” This review discusses the role of androgens in the progression of cardiovascular disease and explores novel therapeutic targets without reporting new clinical results.
610 citations
,
April 2014 in “Nature Reviews Immunology” This review discusses the complex mechanisms regulating skin immunity to balance host defense with inflammation, but reports no new findings.
556 citations
,
September 2008 in “Genes & Development” This review summarizes how genetic studies using conditional β-catenin loss- and gain-of-function mice have advanced understanding of canonical Wnt signaling's role in embryonic development, adult stem cell maintenance, and cancer modeling.
471 citations
,
October 2012 in “Cellular and Molecular Life Sciences” This review discusses the roles of key developmental signaling pathways in mammalian skin repair compared to skin development, and suggests these insights could lead to better wound healing therapies, but it reports no new findings.
466 citations
,
August 2004 in “Journal of the American Academy of Dermatology” This article reviews the current literature on rosacea, focusing on the new subtype classification system and the main theories of its pathogenesis, but reports no new clinical results.
451 citations
,
March 2005 in “Endocrine Reviews” This paper discusses the role of steroid sulfatase in hormone-dependent tumors and highlights the development of potent inhibitors, noting the commencement of a phase I trial for one inhibitor in postmenopausal breast cancer patients.
434 citations
,
October 2003 in “PTR. Phytotherapy research/Phytotherapy research” This review discusses the use of natural products in cosmetic preparations for skin and hair care, but reports no new research results.
425 citations
,
January 2021 in “SN Applied Sciences” This article highlights the versatility and potential of alginate and its derivatives in tissue engineering applications, discussing their properties, modification techniques, and various uses in enhancing tissue healing, bone regeneration, and cell growth.
421 citations
,
January 2015 in “Chemical Society Reviews” This review discusses recent advances in surface modification and endothelialization of biomaterials for vascular grafts, highlighting promising methods like gene engineering and targeting ligand immobilization to improve clinical outcomes.
419 citations
,
January 2015 in “Journal of Consumer Research” This study found that corporate social responsibility can enhance consumer perceptions of product performance, especially when viewed as motivated by genuine benevolence rather than self-interest.
414 citations
,
August 2005 in “The Journal of Clinical Endocrinology and Metabolism” This study estimates the total cost of evaluating and treating polycystic ovary syndrome in reproductive-aged women in the United States to be $4.36 billion, suggesting more liberal screening could be beneficial.
408 citations
,
January 2017 in “Science” This study found that hair follicles in mice and humans can convert wound-related myofibroblasts into adipocytes, suggesting a potential pathway to reduce scar formation by activating BMP signaling.
405 citations
,
May 2007 in “Journal of The American Academy of Dermatology” This review discusses the profound impact of obesity on skin physiology and dermatologic conditions and reports no new experimental results, recommending awareness and treatment strategy development for obesity-associated dermatoses.
403 citations
,
November 2005 in “Journal of Endocrinology” This review discusses the role of DHEA in intracrinology, highlighting its impact on breast and prostate cancer treatment and potential as a menopause therapy, but reports no new research findings.
403 citations
,
December 2018 in “Cell stem cell” This study suggests that phenotypic plasticity, including processes like dedifferentiation and transdifferentiation, plays a crucial role in cancer initiation, progression, and therapy resistance, broadening our understanding of cancer dynamics and potential treatment strategies.
401 citations
,
January 2013 in “Postepy Dermatologii I Alergologii” This review discusses the biology and development of skin melanocytes, but reports no new clinical findings.
384 citations
,
June 2005 in “Genes & development” This study found that stabilized beta-catenin is crucial for activating stem cell transition from quiescence to proliferation in hair follicles by influencing gene expression within the stem cell niche.
351 citations
,
February 2010 in “Nature Cell Biology” Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.
343 citations
,
December 2008 in “Endocrine Reviews” This review discusses the various evidence-based and potential applications of metformin in treating and preventing symptoms and complications associated with polycystic ovary syndrome but reports no new clinical results.