research Menstrual Disorders in Adolescents
The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.
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research Acne in Women
Acne is common in women, often hormone-related, negatively affects quality of life, and requires various treatments.
research Nonfebrile Seizures in Pediatrics: Key Points to Remember
Early diagnosis and treatment of hereditary vitamin D-resistant rickets (HVDRR) are crucial to prevent growth issues and other health problems.
research Antagonism of NMDA Receptors as a Potential Treatment for Down Syndrome: A Pilot Randomized Controlled Trial
Memantine may slightly improve memory in people with Down syndrome, but more research is needed.
research Research Progress of Post-Acute Sequelae After SARS-CoV-2 Infection
Long COVID causes various long-term health issues and needs better awareness and treatment.
research The Ecology of Human Sleep Project: Protocol for a Longitudinal Cohort Repeated-Measurement-Burst Study to Assess the Relationship Between Sleep Determinants and Sleep Outcomes Under Real-World Conditions Across Time of Year
The study aims to understand how mood, physical activity, light exposure, and seasonal changes affect sleep patterns.
research Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research
New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.
research Cure Most Diseases by Logical Nutrition Treatment: The Society Agent Simulating and Usage of Oral and Dental Diseases to Predict Criminals Earlier
The document suggests using natural remedies like bloodletting and honey for various health issues but lacks scientific evidence for their effectiveness.
research Contraceptive Use in Acne
Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.
research A Cross-Cultural Ethnobotanical Knowledge Comparison About Local Plants Among Pashto, Punjabi, and Saraiki Communities Living in Southwest Pakistan
Traditional medicinal plants are still widely used and could help local development and inter-ethnic relationships.
research Immune-Mediated Diseases of the Central Nervous System
The document explains the difficulty in diagnosing and treating brain diseases caused by the immune system and stresses the need for quick and accurate tests.
research Plants Producing Ribosome-Inactivating Proteins in Traditional Medicine
Some plants used in traditional medicine may help treat cancer because they contain proteins that can inactivate ribosomes.
research Altered Resting-State Activity in Seasonal Affective Disorder
People with Seasonal Affective Disorder have different brain activity in certain areas when resting.
research Liver Transplantation for Propionic Acidemia in Children
Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.
research References
research Preparation of Anticancer Extract
Hibiscus micranthus leaf extract is safe and effective for antibacterial and wound healing.
research GABAA Receptor Modulation by Neurosteroids in Models of Temporal Lobe Epilepsies
Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.
research Adverse Side Effects of 5α-Reductase Inhibitors Therapy: Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients
Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.
research Abstracts
New treatments and diagnostic methods for various animal skin conditions showed promising results.
research Traditional Knowledge Digital Library: The Challenges Ahead
The document suggests creating a secure database for indigenous knowledge and recommends that the TKDL actively fight patents that slightly alter traditional knowledge.
research Role of Anticonvulsant and Antiepileptogenic Neurosteroids in the Pathophysiology and Treatment of Epilepsy
Neurosteroids show promise for treating epilepsy and more research is needed.
research Neurosteroid-Sensitive δ-GABAA Receptors: A Role in Epileptogenesis?
Blocking neurosteroid production can lead to more seizures and faster epilepsy onset in rats.
research Inhibitory Influence of Agmatine on Catamenial-Like Seizure Susceptibility in Progesterone Withdrawn Female Rats
Agmatine may help reduce seizures linked to hormone changes in female rats.
research A New Look at the 5-Alpha-Reductase Inhibitor Finasteride
Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
research Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
research Neurotrophin-4 Modulates the Mechanotransducer Cav3.2 T-Type Calcium Current in Mice Down-Hair Neurons
Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.
research Realizing the Therapeutic Potential of Neuroactive Steroid Modulators of the GABAA Receptor
Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.
research A Rare Cutis Verticis Gyrata Secondary to Cerebriform Intradermal Nevus: Case Report and Literature Review
A man's unusual scalp folds caused by a skin condition were treated with surgery and remained unchanged two years later.
research A 10 Mb Duplication in Chromosome Band 5q31.3–5q33.1 Associated with Late-Onset Lipodystrophy, Ichthyosis, Epilepsy, and Glomerulonephritis
A genetic duplication on chromosome 5 was linked to a woman's unique combination of medical conditions.