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This study found that simultaneous inactivation of pRb and p53 genes in mice's epidermis accelerates aggressive squamous cell carcinoma development, highlighting p53 as a key tumor suppressor.

This study found that the simultaneous inactivation of pRb and p53 genes in mouse epidermis accelerated aggressive squamous cell carcinoma development via activation of the epidermal growth factor receptor/Akt pathway.

Hair can regrow in adult mice's skin after injury, and this regrowth doesn't come from existing hair cells but from skin cells in the wound, with Wnt7a protein helping this process. This could help treat baldness and scarring.

This study established a model using nude mice to successfully graft human scalp skin, maintaining hair follicle growth and skin integrity for at least two months, which may aid preclinical research.

This case report provides the first evidence of clinical and histopathological findings of cutaneous diffuse basaloid follicular hamartomas in a young domestic short hair cat.

Keratin 79 cells help form and regenerate hair canals.

Basonuclin is crucial for hair follicle development and cycling in mice.

This study found that squamous cell carcinomas from hair follicle stem cells are more prone to epithelial to mesenchymal transition and metastasis than those from interfollicular epidermis, due to distinct chromatin landscapes.

Fibroblasts can be turned into melanocytes for potential skin treatments.

This review explores how epithelial cells from various niches in the skin respond and adapt during acute wound repair, highlighting the role of cellular plasticity in reepithelialization and restoring the skin's barrier function.

This study observed that erosive pustular dermatosis of the scalp in elderly patients was effectively treated with high-potency topical steroids, with plasma and lymphocyte dermal infiltrates helping to confirm diagnosis.

Wound healing is a complex process involving different cells and stages, leading to scar tissue formation and strength increase over time.

This study suggests that TIP39 and its receptor PTH2R, identified in human epidermis, may play a role in keratinocyte function and influence skin differentiation.

The authors suggest that tooth, dermal scale, epidermal scale, feather, and hair evolved in parallel from a shared placode/dermal cell unit in an early vertebrate gnathostome with odontodes, around 420 million years ago.

This study found that long-term hair follicle stem cells originate from embryonic progenitor cells in a niche with reduced Wnt/β-catenin signaling, which is essential for their specification.

This study found that macroscopic vesiculobullous lesions with epidermal devitalization in dogs are part of the clinical spectrum of canine cutaneous epitheliotropic T-cell lymphoma.

This study identified the placenta at the base of the ovary as the origin of poplar seed hair development and detailed transcriptome dynamics during the growth process.

This research found that Foxc1 is critical for maintaining quiescence in activated hair follicle stem cells and that the cancer cell-of-origin influences tumor heterogeneity in mouse skin squamous cell carcinoma.

The researchers reported that basal cell carcinoma tumor cells strongly express keratins typical of basal keratinocytes and some hair follicle components but lack differentiation markers, suggesting a follicular or pluripotent stem cell origin.

This study reviewed the current state of intralesional therapy for keratoacanthoma, finding that while methotrexate, 5-fluorouracil, and interferon alpha are common agents, guidelines are still needed, and histopathological confirmation is advised to prevent misdiagnosis with squamous cell carcinoma.

This study found that the expression of LRIG1 in Merkel cell carcinoma tumors was associated with improved overall and cancer-specific survival.

In this study, mouse amnion epithelium was successfully transformed into skin and hair follicles when associated with hair-forming dermis, revealing the necessity of specific influences for follicle formation.

This study found that wound healing after CO(2) laser resurfacing is faster with occlusive dressings, as they enhance cell migration from hair follicles, compared to untreated skin, which showed delayed re-epithelialization.

This article provides issue information and does not include an abstract or any new research findings.

Basonuclin helps identify and track hair follicle development and cycling in mice.

This study found no qualitative skin differences during development between mutant hairless USP mice and BALB/c mice, except for enlarged cysts in the hairless strain.

In this study, researchers described dermatophylosis in sheep from Northeast Brazil, observing sporadic cases marked by alopecic and crusty skin lesions, affecting both adult males and females primarily in April, June, and November.

This review discusses the pathophysiology of psoriasis and available treatment options but reports no clinical trial results.

This review discusses recent advances in using stem cells for skin repair and regeneration after severe burn injuries, but it reports no new clinical results.

New therapies for burn wounds show promise in reducing pain, infection risk, and improving healing and physical outcomes.