2 citations
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April 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that vitamin D receptor presence is vital for normal hair growth in mice, as shown by vitamin D receptor-null mice developing alopecia, while transgenic expression of human vitamin D receptor in these mice restored normal hair growth.
May 2015 in “Journal of the American Academy of Dermatology” Certain drugs and supplements may contribute to hair loss in the frontal hairline in older women.
1 citations
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September 2001 in “PubMed” This review discusses the effectiveness and risks of acitretin in treating various skin conditions, highlighting its teratogenic potential and the necessary precautions for its use.
53 citations
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October 2014 in “Free radical biology & medicine” This study found that oxidative damage is present in the mitochondria of PolG mice, which exhibit premature aging-like phenotypes due to mitochondrial dysfunction.
75 citations
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January 2014 in “Korean Journal of Urology” This review discusses the adverse effects of 5α-reductase inhibitors, finasteride and dutasteride, on sexual, psychological, and vascular health, emphasizing the need for physicians to inform patients of these risks.
January 2014 in “edoc (University of Basel)” This research suggests that fluoxymesterone, an anabolic steroid, may inhibit a key enzyme, potentially contributing to cardiovascular issues by affecting cortisol's activation of mineralocorticoid receptors.
May 2007 in “Proceedings of the National Academy of Sciences of the United States of America” Alexander the Great's engineers built a causeway using a natural sand bridge, some tiger moths avoid bats by mimicking toxic relatives' sounds, early metabolism and RNA enzymes support the ancient RNA world theory, and vitamin D is crucial for hair growth and its absence can cause baldness.
January 2021 in “Middle East journal of applied sciences” This article discusses the widespread issue of zinc deficiency affecting plant, animal, and human health, and reports no new clinical results; the authors emphasize the need for adequate zinc availability in agriculture and nutrition.
January 2014 in “Jaypee Brothers Medical Publishers (P) Ltd. eBooks” Finasteride can cause side effects like liver issues and hormonal changes.
4 citations
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October 2022 in “Evidence-based complementary and alternative medicine” This study found that Ficus carica extract enhanced fertility markers, including hormone levels and reproductive organ activity, in rats of both sexes, suggesting potential benefits for managing fertility issues.
3 citations
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August 2019 in “Journal of Animal Physiology and Animal Nutrition” This study found that the combined use of sugarcane fibre and keratinolytic enzymes reduced hairball excretion in cats.
1 citations
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November 1988 in “Veterinary Record” In this case study, oral folic acid therapy resulted in noticeable improvement and eventual recovery from hair loss and skin issues in a three-week-old Charolais calf.
17 citations
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January 2020 in “The World Journal of Men's Health” This article discusses the potential health risks associated with long-term use of finasteride and dutasteride for prostate and hair loss treatments, suggesting risks may include non-alcoholic fatty liver disease, insulin resistance, type 2 diabetes, and other metabolic issues.
8 citations
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July 1977 in “Lipids” This study found a negative correlation between dietary monoene levels, particularly oleic acid, and the capacity for PGE₂ synthesis in rat skin, with the most severe skin issues noted in those fed Zephyr rapeseed oil.
January 2025 in “Open Veterinary Journal” This study found that sheep with deficiencies in zinc, copper, and vitamin A exhibited symptoms like weight loss, skin disorders, and abnormal hematological and antioxidant enzyme levels compared to healthy sheep, suggesting that dietary supplementation of these nutrients could prevent these health issues.
May 2024 in “Trends in endocrinology and metabolism” This research review discusses how iron deficiency affects various bodily functions and systems, such as immunity and metabolism, by identifying the iron-dependent enzymes and pathways involved, suggesting that understanding these mechanisms may offer new treatment possibilities for related diseases.
69 citations
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December 2005 in “Nature Clinical Practice Endocrinology & Metabolism” Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.
19 citations
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September 2013 in “Psychoneuroendocrinology” Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.
1 citations
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August 1984 in “Therapeutische Umschau. Revue thérapeutique” This article reviews treatments for facial hypertrichosis and hirsutism and reports no new clinical findings; the authors highlight the potential of laser and pulsed flash-light systems for permanent hair removal.
46 citations
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July 2010 in “Advances in Therapy” SPET-085 effectively inhibits an enzyme linked to prostate issues, similar to finasteride.
15 citations
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March 2015 in “Experimental Dermatology” Clotrimazole, an antifungal cream, may safely reduce skin pigmentation by breaking down the enzyme needed for making melanin.
November 2011 in “ChemInform” Finasteride effectively treats hair loss and prostate issues by blocking a specific enzyme.
97 citations
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May 2008 in “Journal of Cutaneous Pathology” This review highlights the challenges in identifying histological features of adverse reactions to soft tissue fillers and emphasizes the need for increased awareness due to product uncertainty and delayed reactions.
5 citations
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December 2014 in “Polish Journal of Public Health” This review discusses the mechanisms of zinc transport, its role in human health, and the effects of zinc imbalance, without reporting new results.
This study developed a three-dimensional model for studying hair follicle development, showing that immortalized dermal papilla cells retain certain differentiation activities and can induce tubule formation in vitro.
research ACNE
58 citations
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January 1997 in “Dermatologic Clinics” This study found that daily consumption of soft drinks significantly increases the risk of moderate-to-severe acne in adolescents, particularly if sugar intake from these drinks exceeds 100 grams per day.
24 citations
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September 2023 in “Science Advances” In this study, deleting the gene Mettl3 in mouse epidermal progenitors resulted in impaired epithelial development and self-renewal, highlighting m6A's crucial role in regulating chromatin modifiers and maintaining normal epithelial tissue function.
16 citations
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September 2008 in “Dermatologic Therapy” This review discusses the clinical features, genetics, and treatment of 21-hydroxylase deficiency, a common type of congenital adrenal hyperplasia, and reports no new research findings.
3 citations
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November 2019 in “Clinical psychopharmacology and neuroscience/Clinical Psychopharmacology and Neuroscience” Valproate can cause both hair loss and curly hair in bipolar disorder patients.
1 citations
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June 2019 in “Current developments in nutrition” This case study reports that pancreatic enzyme replacement and fatty acid supplementation improved symptoms of fat malabsorption and essential fatty acid deficiency in a patient with EDS-4.