research Advances in Nucleoside Monophosphate Prodrugs as Anti-HCV Agents
New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.
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research Androgen Receptor Antagonists Structure-Activity Relationships
Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.
research Phytochemical Studies on Traditional Herbal Medicines Based on Ethnopharmacological Information Obtained by Field Studies
Over 150 new molecules with biological activities were found in traditional herbal medicines, some with potential for new drug development.
research Finasteride: The First 5α-Reductase Inhibitor
Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
research A Keratinocyte-Specific Epoxygenase, CYP2B12, Metabolizes Arachidonic Acid with Unusual Selectivity, Producing a Single Major Epoxyeicosatrienoic Acid
CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.
research Influence of Chemical Straightening on the Stability of Drugs of Abuse in Hair
Chemical hair straightening significantly reduces detectable drug levels in hair.
research Limits of Visual Detection for Finasteride Polymorphs in Prepared Binary Mixtures: Analysis by X-ray Powder Diffraction
research Phenomenology of Polymorphism: The Topological Pressure–Temperature Phase Relationships of the Dimorphism of Finasteride
Finasteride's two forms have different stability based on temperature and pressure.
research Properties and Applications of Nanoparticles and Nanomaterials
Nanoparticles have diverse applications, including promising cancer treatments and hair growth solutions.
research Structural Study of Polymorphs and Solvates of Finasteride
Different forms of hair loss drug can improve effectiveness.
research Evaluation of Biological Activity Exerted by an Aza-Bicyclocarboxylic Acid Derivative Using an Ischemia-Reperfusion Injury Model
Compound 3 protects the heart from damage by activating A1-adenosine receptors.
research In Vitro and In Silico Evaluation of Toxicological and Anti-Proliferative Activity in Phytochemical Compounds of Several Solvent Extracts from Zaleya Pentandra L
Zaleya pentandra extracts, especially acetone, may be useful for new medicines and food industry applications.
research Biotin - Facts and Hopes
Biotin is important for health, but taking extra usually doesn't help unless you're deficient.
research Composite Hydrogels with Embedded Silver Nanoparticles and Ibuprofen as Wound Dressing
The hydrogel with silver and ibuprofen promotes wound healing and fights infection.
research From Plants to Wound Dressing and Transdermal Delivery of Bioactive Compounds
Plant-based compounds can improve wound dressings and skin medication delivery.
research Role of Scalp Health in Achieving Optimal Hair Growth and Retention
Healthy scalp leads to better hair quality and less damage.
research A Multi-Technique Approach to the Study of Structural Stability and Desolvation of Two Unusual Channel Hydrate Solvates of Finasteride
Desolvation of finasteride depends on environment and technique.
research Recent Advances in Thiasteroids Chemistry
New sulfur-containing steroid analogs show promise for more targeted medical treatments.
research In Vitro and In Vivo Structure-Activity Relationships of Novel Androgen Receptor Ligands with Multiple Substituents in the B-Ring
Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.
research Scalp Condition Impacts Hair Growth And Retention Via Oxidative Stress
Healthy scalp reduces hair loss by managing oxidative stress.
research A New Catalyst for Organic Synthesis: Mercuric Triflate
Mercuric triflate is an effective catalyst for various organic reactions, working well at room temperature with high yields.
research Quality Evaluation of the Finasteride Polymorphic Forms I and II in Capsules
Finasteride's polymorphic form affects capsule quality and drug effect, requiring strict control.
research Insight into Recent Advances in Degrading Androgen Receptor for Castration-Resistant Prostate Cancer
New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.
research Efficacy and Tolerability of a Shampoo Containing Broad-Spectrum Cannabidiol in the Treatment of Scalp Inflammation in Patients with Mild to Moderate Scalp Psoriasis or Seborrheic Dermatitis
A shampoo with cannabidiol can significantly reduce scalp inflammation and symptoms in people with mild to moderate psoriasis or seborrheic dermatitis.
research Bioactive Compounds from the Roots of Asiasarum Heterotropoides
Two compounds from Asiasarum heterotropoides roots show potential as lung cancer treatments without harming normal cells.
research Phytochemical, Toxicological and Pharmacological Studies of Asiasari Radix et Rhizoma: A Review
Asiasari Radix et Rhizoma is safe and has potential for new drug development due to its therapeutic properties.