April 2024 in “Pigment cell & melanoma research” This study explored the diversity of melanocyte stem cell subpopulations in the hair follicles of adult female mice and identified novel groups with distinct immune privilege regulation, suggesting a heterogeneous landscape that future research should consider.
This study identified the TALE homeodomain transcription factor Meis2 as a crucial regulator for the maturation and end-organ innervation of certain mechanoreceptors in mice, with its absence leading to altered sensory neuron structure and impaired touch sensitivity.
5 citations
,
December 2014 in “Molecular cytogenetics” This study identified a 290 Kb microduplication in chromosome 1q22 in a family with members exhibiting neurodevelopmental disorders, suggesting a link between this genetic alteration and the observed neurological symptoms.
2 citations
,
June 2023 in “Plants” This paper reviews extraction methods for obtaining polysaccharides from brown macroalgae like Sargassum, highlighting their antiviral, antimicrobial, and antitumoral bioactivities in both in vivo and in vitro studies, while also discussing challenges in research and commercialization of Sargassum-based products.
August 2025 in “Dermatopathology” This study identified 96 cases of pilomatricomas linked to genetic syndromes, including a novel association with Apert syndrome, highlighting that these tumors often manifest as the first indication of underlying conditions in pediatric patients.
In this study, researchers developed a method for high-resolution live imaging of leg regeneration in the crustacean Parhyale hawaiensis, which effectively captures the entire process at cellular resolution over 10 days while minimizing photodamage.
51 citations
,
March 1986 in “Acta Dermato Venereologica” This study found no differences in trace element concentrations between Finnish alopecia patients and the normal population, but noted significant serum copper variation among different alopecia subtypes.
July 1993 in “Journal of Radioanalytical and Nuclear Chemistry” Mouse hair element patterns vary, making it unreliable for tracking time.
188 citations
,
May 2009 in “Plant physiology” This study identified 19 specific genes involved in root hair growth and morphogenesis in Arabidopsis, using a combination of computational and experimental methods.
109 citations
,
January 1980 in “Science of the total environment” This paper reviews chemical analysis methods for trace elements in human hair and supports a no-wash policy due to challenges in distinguishing between endogenous and exogenous element sources.
42 citations
,
June 2002 in “Molecular and Cellular Biology” In this study, researchers identified distinct chromatin regions and regulatory elements that drive keratinocyte-specific gene expression, highlighting complex enhancer modules influencing skin epithelium through a combination of transcriptional activators and repressors.
25 citations
,
January 1992 in “International Journal of PIXE” This review discusses medical conditions and therapies related to various elements, such as zinc, copper, mercury, cadmium, lead, chromium, and arsenic, without reporting new experimental results; it highlights past findings on deficiencies, toxicities, and historical cases.
18 citations
,
December 2010 in “Journal of Trace Elements in Medicine and Biology” This study suggests that alterations in copper metabolism may play a key role in the development of androgenetic alopecia in women, presenting potential targets for treatment strategies.
9 citations
,
August 2020 in “Ecological indicators” This study in western Hudson Bay, Canada, examined trace elements in the hair of adult male polar bears and found significant differences in concentration patterns along the hair length, suggesting laser ablation ICP-MS is a promising tool for monitoring these variations over time.
9 citations
,
January 2013 This study found that serum levels of zinc, copper, and selenium were significantly lower in patients with alopecia areata compared to healthy controls, regardless of the number of hair loss patches.
8 citations
,
November 2023 in “Frontiers in Bioengineering and Biotechnology” This article reviews recent developments in microneedles combining metallic elements and herbal compounds for wound healing, highlighting their benefits such as enhanced therapeutic efficacy and reduced toxicity, and offering a reference for future advancements in this technology.
7 citations
,
July 2008 in “Experimental Dermatology” This study identified molecular elements controlling the expression and stabilization of THH protein in hair follicle cells, revealing key mechanisms that support hair shaft development in mice.
6 citations
,
January 2018 in “PubMed” This study suggests that elevated levels of certain heavy metals, rather than zinc, may play a causative role in primary chronic telogen effluvium.
5 citations
,
January 1997 in “Journal of Occupational Health” The method effectively maps lead and zinc in hair, aiding understanding of heavy metal exposure risks.
4 citations
,
January 2023 in “Frontiers in Medicine” This review discusses the use of zinc supplementation in dermatology for various skin conditions and reports no new clinical results, providing references for its application.
3 citations
,
April 2023 in “Journal of Veterinary Internal Medicine” This study found that dogs with idiopathic epilepsy had altered hair concentrations of several trace elements, which may suggest a role in the disease's pathophysiology and indicate effects from antiseizure medications.
2 citations
,
June 2016 in “Russian Journal of Skin and Venereal Diseases” This study reported a decrease in zinc and iron levels in the blood and an increase in certain trace elements in hair among patients with alopecia areata compared to healthy individuals.
1 citations
,
August 2023 in “International journal of pharmacy & integrated health sciences” This review discusses various bioactive elements in cosmeceuticals, highlighting their potential benefits, such as anti-aging effects and skin tone improvement, while noting the growing demand due to safety concerns and expanding market opportunities.
1 citations
,
January 2021 in “Journal of Dhaka Medical College” This study found a negative correlation between serum iron levels and the duration of hair loss in patients with alopecia.
1 citations
,
December 2015 in “Lʹvìvsʹkij klìnìčnij vìsnik” This review discusses the connection between alopecia areata and trace element imbalances, noting deficiencies in elements like zinc and selenium, but reports no new clinical findings.
1 citations
,
January 2015 in “Trace Elements in Medicine (Moscow)” This case study reports that different organs, such as hair and stature, may grow at varying rates during different stages of growth.
1 citations
,
August 2012 in “Journal of Emerging Trends in Engineering and Applied Sciences” This study found that smoking may lead to earlier onset of androgenetic alopecia in Nigerian subjects, potentially mediated by alterations in serum trace elements.
This study found that telogen effluvium is strongly linked to lower serum levels of ferritin and vitamin D, especially in predominantly female patients.
November 2025 in “Physics of Fluids” In this study, low-intensity ultrasound was investigated as a noninvasive method for promoting hair regrowth in androgenetic alopecia using C57BL/6 male mice, revealing that specific frequencies and intensities can safely enhance hair regrowth compared to controls by optimizing mechanical effects without causing unsafe cavitation.
June 2024 in “Research Square (Research Square)” This study found that women experiencing hair loss post-COVID-19 showed significantly decreased serum copper levels, suggesting potential further research into copper supplementation for preventing and treating post-COVID-19 alopecia.