125 citations
,
August 2003 in “Development” In this study, mice engineered to express human EGFR showed tissue-specific growth defects and neurodegeneration rescue, but developed severe heart issues and accelerated bone cell differentiation.
61 citations
,
April 2023 in “Advanced Materials” This study introduced a viscoelastic dry electrode that successfully reduces motion artifacts in EP monitoring on hairy skin, maintaining stable performance for up to 48 days.
1 citations
,
January 2022 in “Wiadomości Lekarskie” In this study, GERD symptoms were found to be significantly related to acid exposure time and the intensity of excessive daytime sleepiness, which depends on circulating ghrelin levels.
3 citations
,
January 1977 in “Electroencephalography and Clinical Neurophysiology”
August 1994 in “Molecular Endocrinology” This study found that AtT-20 pituitary cells with higher cAMP-dependent kinase activity had larger calcium currents and significantly increased beta-endorphin release compared to cells with lower kinase activity.
February 2013 in “Journal of the American Academy of Dermatology” In this study, the HairCheck device was reported to accurately assess changes in hair density and diameter, suggesting its usefulness in monitoring alopecia progression and treatment response.
38 citations
,
February 2012 in “Supportive Care in Cancer” Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.
7 citations
,
March 2020 in “Journal of the American Academy of Dermatology” This study observed that trichoscopic changes associated with EGFRI treatment include pili torti and asymmetric hyperpigmented fusiform widening, along with dermoscopic skin manifestations such as scale and branching vessels.
3 citations
,
June 2015 in “Serbian Journal of Dermatology and Venereology” In this study, secondary syphilis presented diverse clinical manifestations, with syphilitic alopecia occurring only in HIV-positive patients, underscoring the importance of considering syphilis in differential diagnoses for vulnerable populations.
22 citations
,
February 2007 in “Developmental neurobiology” This study found that variations in Kv1 channel gene expression in the electric organ of Sternopygus correlate with sex differences and individual variations in their electric communication signals.
2 citations
,
January 2019 in “Annals of Dermatology” Certain gene variations in EGF and EGFR may increase the risk of alopecia areata in Koreans.
8 citations
,
August 2018 in “Drug testing and analysis” This study observed that ethyl glucuronide (EtG) concentrations in hair decreased significantly during an abstinent period, suggesting possible wash-out effects or other factors affecting EtG levels.
48 citations
,
March 1993 in “The Laryngoscope” This study found that EGF receptors are aberrantly regulated and persist in cholesteatoma epithelium, suggesting a hyperproliferative character compared to normal human skin.
20 citations
,
November 1968 in “The Lancet” This study found that during dialysis, lower plasma-potassium levels were associated with hyperglycemia, suggesting potassium correction is vital when using glucose-rich dialysate.
3 citations
,
June 2022 in “e-Journal of Cardiovascular Medicine” This study found no significant difference in the ability of ischemia modified albumin and exercise electrocardiograms to determine myocardial ischemia in patients with stable angina pectoris.
June 2024 in “Journal of Clinical Oncology” This study examined the FDA Adverse Events Reporting System and found new dermatologic adverse events associated with EGFR-TKIs in non-small cell lung cancer patients, such as specific skin, nail, and hair issues, that aren't currently listed on drug labels.
October 2018 in “Journal of Clinical Research in Pediatric Endocrinology” This study found that children with classic congenital adrenal hyperplasia had elevated epicardial fat thickness, which was associated with increased carotid intima media thickness, left ventricular mass, and mitral deceleration time.
1 citations
,
November 2001 in “Acc Current Journal Review” This review found that 5α‐reductase inhibitors were associated with slightly increased rates of decreased libido, erectile and ejaculatory dysfunction, gynecomastia, and mood disorders compared to placebo, though their long-term effects remain unclear.
12 citations
,
November 2022 in “Toxics” This review describes how liver and kidney diseases and diabetes may affect ethyl glucuronide levels in hair, impacting forensic and clinical interpretations, but reports no new experimental results.
3 citations
,
August 2013 in “Journal of the American Academy of Dermatology” This study identified a novel microscopic "arrow sign" in hair root sheaths of patients on EGFR inhibitors, potentially aiding in diagnosing related hair changes and differentiating from fungal infections.
January 2022 in “Social Science Research Network” This study found that most potassium channel blockers increased the activity of slowly adapting mechanoreceptors in rat whisker pads, while the opener NS1619 decreased their evoked activity.
9 citations
,
February 2019 in “Journal of Clinical Research in Pediatric Endocrinology” In this study, children with classical congenital adrenal hyperplasia were found to have increased epicardial fat thickness, which was associated with subclinical atherosclerosis markers and left ventricular dysfunction, especially in poorly controlled cases.
12 citations
,
August 2001 in “PubMed” This study found that contrast enhanced phototrichogram (CE-PTG) significantly improved detection of various hair types and growth stages in androgenetic alopecia compared to standard PTG and was comparable to biopsy analysis.
1 citations
,
September 2021 in “Physiology News” The abstract contains only graphic design specifications and reports no new research findings.
22 citations
,
May 2002 in “Skin Research and Technology” This study found that in male androgenetic alopecia, the contrast enhanced phototrichogram technique was superior in detecting changes in hair density and thickness compared to other methods.
July 2014 in “Acupuncture & electro-therapeutics research” This study observed that certain changes in facial "heart representation areas," like eyebrow hair whitening and loss, are associated with cardiovascular issues and may correspond with increased Cardiac Troponin I levels.
66 citations
,
August 1999 in “The Journal of Clinical Endocrinology & Metabolism” This study found that menstrual irregularity is common in women with acromegaly, with high GH levels, estrogen deficiency, and larger tumors correlating with more severe irregularity.
1 citations
,
December 2016 in “Journal of Evolution of Medical and Dental Sciences” This study found significant associations between pruritus and elevated parathormone levels, and xerosis and elevated serum creatinine levels, in chronic kidney disease patients undergoing haemodialysis.
April 2016 in “Plastic and reconstructive surgery. Global open” This abstract catalogs resources from the American Society of Plastic Surgeons but presents no research findings.
7 citations
,
January 2009 in “BMJ Case Reports” This report describes a rare case of a non-small-cell lung cancer patient experiencing hair changes after prolonged gefitinib treatment, potentially linked to EGFR inhibition, with limited understanding of its cause.