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In this study, low doses of cyproterone acetate with ethinylestradiol were as effective as low-dose flutamide in reducing acne severity in hyperandrogenic women, while finasteride was less effective.

This study surveyed dermatologists and found that Doxepin was the most preferred anti-depressant for treating psycho dermatoses in elderly patients.

Dutasteride is more effective for male pattern baldness than finasteride, and black cohosh extract BNO 1055 is as effective as conjugated estrogens in treating postmenopausal symptoms, with added benefits in reducing sweating and mental symptoms.

In this study, tofacitinib showed promising efficacy and safety for biologic-naïve elderly patients with moderate-to-severe ulcerative colitis, achieving steroid-free remission and clinical response over 52 weeks.

This case report highlights the growing trend of adolescents using Finasteride off-label for early hair loss, driven by online misinformation and psychological distress, despite potential side effects and hormonal concerns.

A new compound may effectively inhibit the enzyme linked to BPH and hair loss.

In this study, high-dose dutasteride significantly reduced several core symptoms of PMDD compared to placebo, supporting the role of neurosteroids in this condition.

This study concluded that finasteride 1 mg does not significantly affect the metabolism of omeprazole in young healthy Japanese male extensive or poor metabolizers for CYP2C19.

This study suggests that neurosteroids and compounds acting on GABA(A) receptors, like THIP, may modulate ethanol intake by influencing drinking patterns.

This article reviews the reported sexual and psychological side effects of 5-alpha reductase inhibitors for benign prostatic hyperplasia, emphasizing the need for further clinical studies.

This article contains additional supporting information available online but presents no new research findings.

This study found that combining topical eflornithine with triple diode laser treatments in women with hirsutism led to a more rapid and nearly complete reduction of terminal hair after 6 months, though the intergroup differences were not significant at 6- and 12-month follow-ups.

This review discusses the psychological and social challenges of hirsutism in women and suggests that eflornithine cream may offer a small quality of life improvement for affected individuals, though with limited evidence.

This policy brief highlights that post-drug syndromes remain under-recognized in pharmacovigilance, leading to inadequate risk assessments and patient care. It identifies systemic failures in current frameworks and recommends actions to improve long-term drug safety monitoring and education, affecting public health outcomes significantly.

Finasteride and dutasteride increase sexual dysfunction reports.

Tamsulosin works faster, but both drugs have similar effects after 6 months.

Old drugs are often used for new, different medical purposes in endocrine pharmacology.

This study found that a topical transethosomal system may enhance the skin penetration and deposition of naftifine compared to a marketed cream, potentially overcoming the stratum corneum barrier.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

This article highlights the importance of recognizing, preventing, and reporting adverse drug reactions to the FDA's MedWatch program, but it presents no new research findings.

This study discovered that the disposition of LY191704 enantiomers in rats and dogs is both stereoselective and species specific.

This study validated a precise and sensitive reverse phase high performance liquid chromatographic method for determining Finasteride and Tamsulosin concentrations in bulk and tablet forms, with satisfactory accuracy and reproducibility.

Researchers developed a quick and sensitive way to measure finasteride in blood using a small sample size.

In this study, G. brevis and M. myristica, alone or together, improved hematological and testicular antioxidant parameters in male rats with finasteride-induced reproductive toxicity, showing potential protective effects against oxidative stress and supporting therapeutic use for related male reproductive disorders.

This study observed that finasteride, while lowering cholesterol levels, did not decrease the prevalence of clinical cardiovascular events or new ECG abnormalities in men with benign prostatic hyperplasia compared to controls, suggesting a potential disconnect between cholesterol management and cardiovascular risk reduction with this treatment.

This review reported that spironolactone, used off-label, is an effective and safe treatment option for adult women with acne, presenting fewer adverse reactions compared to common treatments like antimicrobials, which carry the risk of microbial resistance.