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The April 2014 issue of "Fertility and Sterility" discussed various reproductive health topics, including hormone therapy benefits, sperm and genetic factors in male infertility, and the link between PCOS and diabetes.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

The document concludes that accurate diagnosis and management of PCOS are crucial due to its associated health risks.

Metformin is safe in early pregnancy for women with PCOS and may reduce certain risks.

A Shi Tzu dog with high cortisol levels improved after increasing the dose of trilostane.

Eating disorders can cause various hair problems, and while hair loss in these disorders is linked to metabolic syndrome, treatment focuses on specific medications and lifestyle changes for the syndrome.

Hormonal contraceptives are effective for teens but require careful consideration of side effects and individual health.

The regenerative medicine industry saw business growth with new partnerships, clinical trials, and financial investments.

Hirsutism is often caused by high male hormone levels and can be treated with lifestyle changes and medications.

Certain hairstyles can cause scalp diseases, smoking is linked to hair loss, 5% minoxidil foam is effective for hair loss treatment, and various factors influence wound healing and hair growth.

The document reports unique growth lines in a child after Stevens-Johnson syndrome, skin reaction from parsnips and sun in a girl, and itchy skin with xanthomas in a boy with Alagille syndrome.

Alopecia areata in infants may be more common than previously thought.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.

Oxygen levels can drop during liver transplant if bypass pressures are too high, but other reasons should be checked first.

The book is a valuable reference on androgenic disorders for professionals but not suitable for laypeople or medical students.

Minoxidil showed a 30% success rate for hair growth in a study, and various skin treatments were effective, but some had limitations or side effects.

The reply suggests checking for false positive or asymptomatic syphilis and using penicillin for treatment if necessary.

Skin changes in Pseudoxanthoma elasticum patients can indicate the severity of related health issues.

High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

New treatments for the autoimmune hair loss condition alopecia areata may include JAK inhibitors and other immunomodulators.

A specific molecular switch, driven by MAPK/ERK signaling, helps spiny mice heal wounds by regenerating skin instead of forming scars.

Msx2 deficiency in mice leads to bone growth and organ development problems.

YAP and TAZ are crucial for skin cell growth and repair.

Balanced vitamin D levels are crucial to delay aging and prevent related diseases.

The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.

Noggin gene inactivation causes skeletal defects in mice, varying by genetic background.

Deleting part of a gene in mice causes wavy hair and high pup loss.

Blocking the ATX-LPA pathway may improve insulin sensitivity and mitochondrial function in obesity.

Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.