March 2026 in “Dyes and Pigments” This study found that genipin-based pigments, accelerated by riboflavin and blue-light photocatalysis, achieved commercial-level hair dye results with enhanced gloss and excellent color retention while reducing cuticle disruption, offering a potentially safer and faster alternative to traditional hair coloration methods.
January 2026 in “Medicina” This study conducted among medical students in Saudi Arabia found a 37.2% prevalence of premature hair graying and associated it with smoking, a keto diet, hair coloring, and family history, while suggesting that lifestyle changes may reduce its impact.
January 2026 in “Journal of Pregnancy” This study suggests a potential link between hair dye exposure during periconception or pregnancy and certain adverse obstetric and pediatric outcomes, but the evidence remains preliminary and uncertain.
December 2025 in “Applied and Computational Engineering” In this study, researchers explored the potential allergenicity and harmful effects of hair dyes, noting that adverse effects such as sensitization and potential carcinogenicity are not inevitable and can vary based on individual physiological differences.
December 2025 in “Journal of Pharma Insights and Research.” This study explains the formulation and evaluation of a natural polyherbal shampoo, which effectively colors hair and provides conditioning without the dermal and systemic toxicity risks of synthetic dyes, offering an effective alternative to conventional products.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this review, the authors highlight the growing use of herbal cosmetics in the personal care industry due to their health benefits, emphasizing the importance of quality control and safety in these increasingly popular natural formulations.
November 2025 in “International Journal of Science and Research Archive” This study reviews how different hair dyeing methods affect hair structure, showing oxidative dyes cause more structural damage than semi-permanent dyes, while new technologies aim to minimize harm while preserving color.
June 2025 in “Samarra Journal of Pure and Applied Science” This study developed a rapid and accurate spectrophotometric method using diazotized sulfanilic acid to measure minoxidil in both pharmaceutical formulations and pure form, demonstrating high precision and linearity within a concentration range of 5-40 μg/ml.
March 2025 in “Digital Library of Theses and Dissertations (Universidade de São Paulo)” In this study, the researchers observed that ferulic acid and resveratrol effectively protected chemically treated hair from oxidative damage, particularly against protein loss and color degradation, but not cisteine oxydation prevention, and these antioxidants also offered protection against sun-induced damage when used in conditioners.
November 2024 in “Jurnal Biomedika dan Kesehatan” This study explores premature graying of hair, outlining potential causes such as genetic factors, nutritional deficiencies, and autoimmune disorders, and evaluates various management strategies including nutritional supplements, pharmacotherapy, and addressing underlying conditions.
November 2024 in “Majalah Farmasetika” In this study, the researchers explored a hair dye gel formulated with Indonesian native plant extracts and found it produced stable brown shades on bleached hair, with the most preferred dark brown achieved at a 12% concentration, and showed no skin irritation.
November 2024 in “International Journal of Dermatology” This study observed that in a survey of individuals with scarring alopecia, those using chemical treatments or high-tension hairstyles experienced hair loss and alopecia diagnosis at a younger age, while hair dye use was linked to older age at hair loss onset and diagnosis.
November 2024 in “Dermatitis” This review identifies specific personal care products and allergens commonly causing allergic contact dermatitis in men, which may improve diagnosis and treatment.
October 2024 in “UNESP Institutional Repository (São Paulo State University)” This study investigated the effects of ammonium thioglycolate and amino methylpropanol hair straightening followed by permanent coloring, finding significant physical and chemical changes to both the cuticle and cortex of hair fibers.
September 2024 in “Heliyon” In this study, researchers observed that even a single session of hair dyeing can damage hair fibers, with significant worsening of mechanical properties and protein composition after three or more consecutive treatments, emphasizing the need to consider the cumulative impacts of dyeing on hair health.
June 2024 in “Journal of Clinical Medicine” This case study and literature review highlights a chemical burn from hair dye experienced by a 17-year-old girl, resulting in a long-term scalp ulcer. It emphasizes the need for careful consideration of scalp complications and a multidisciplinary treatment approach in hair dye procedures.
In this study, researchers found a strong association between premature graying of hair and deficiencies in vitamin D and B12, hypothyroidism, and deranged iron profiles, along with higher stress, altered appetite, smoking, and sleep pattern issues, significantly impacting quality of life.
September 2023 in “Journal of the American Academy of Dermatology” This meta-analysis found a significant positive association between frontal fibrosing alopecia and both sunscreen and moisturizer use, with the moisturizer association significant only in males.
May 2023 in “Sokoto journal of medical laboratory science” This study demonstrated that prolonged use of commercial hair dyes caused significant increases in liver enzymes and bilirubin levels, and evident cellular injury in the skin and liver tissues of Albino rats, indicating potential toxicity.
April 2023 in “Journal of Investigative Dermatology” This study developed a new quantitative method to measure skin cell turnover in just 4 days, showing it can effectively differentiate skincare product performance and revealing that turnover slows with age but responds more to treatments as people get older.
November 2022 in “Journal of Investigative Dermatology” This study identified 15 Iranian patients with PLEC variants linked to various plectinopathies and highlighted a novel association between a homozygous nonsense variant in PLEC and a rare combination of disorders including EB pruriginosa, muscular dystrophy, and congenital myasthenic syndrome.
February 2022 in “Research Journal of Biotechnology” This review discusses the taxonomy, traditional uses, and pharmacological activities of the medicinal plant Eclipta alba but reports no new clinical findings.
February 2022 in “arXiv (Cornell University)” This study introduces a novel method for capturing and digitally rendering the color appearance of physical hair samples using deep neural networks.
August 2021 in “Annals of Agricultural and Environmental Medicine” This review provides a detailed analysis of frontal fibrosing alopecia, focusing on its prevalence in postmenopausal Caucasian women, associated comorbidities, and potential autoimmune, genetic, hormonal, and environmental factors; it emphasizes the need for improved understanding to enhance diagnosis and treatment.
July 2021 in “British Journal of Dermatology” Laser treatment for skin conditions VEN and ILVEN is effective and liked by patients.
September 2020 in “Benha Journal of Applied Sciences” This study found that scanning electron microscopy revealed significant hair shaft changes in women using straighteners, but not in those using hair dye, suggesting its utility in assessing chemical treatment effects on hair.
This chapter discusses pediatric disorders like alopecia areata and vitiligo, identifying laser and light therapies as treatment options, and highlights that the pulsed dye laser is well tolerated and effective for treating molluscum contagiosum.
December 2017 in “JURNAL FARMANESIA” In this study, the researchers found that using dragon fruit peel extract in a gray hair dye formulation, along with specific adjuvants, produced a dark black color on gray hair, demonstrating its potential as a natural colorant alternative to synthetic dyes.
April 2017 in “InTech eBooks” This review discusses potential mechanisms and treatments for trichodynia, noting a lack of strong literature support and reporting no new clinical results; the authors highlight several hypotheses and available treatment options.
November 2016 in “University of the Arts London Research Online (University of the Arts London)” This study concluded that adding polymeric conditioning actives to shampoos improved color retention in permanently dyed hair, while additional cationic dyes at certain pH levels weakly dyed the hair directly.