50 citations
,
May 2020 in “Journal of Clinical Medicine” This review highlights the need for tailored hormonal treatment strategies for non-binary transgender individuals, emphasizing personalized care to enhance psychological well-being and quality of life.
1 citations
,
July 2015 in “The European research journal” This case report describes reversible hair loss in a patient taking aripiprazole, suggesting this side effect may be common among psychotropic medications.
4 citations
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August 2021 in “Biomedicine & Pharmacotherapy” This review summarizes the association between 5-alpha reductase inhibitors and depression, discussing potential mechanisms such as neuroactive steroid alterations and neuroinflammation, but reports no new clinical results.
1 citations
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July 2018 in “Current Sexual Health Reports” This review discusses the occurrence of persistent sexual, physical, neurological, and psychiatric side effects known as post-finasteride syndrome after 5x-reductase inhibitor treatment, and emphasizes the importance of evaluating these risks for patients with benign prostatic hyperplasia or androgenic alopecia.
82 citations
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August 2006 in “Pharmacology, Biochemistry and Behavior” This review proposes focusing on relationships between neuroactive steroids and psychiatric disorder symptoms, rather than relying on traditional disorder classifications, and reports no new clinical findings.
59 citations
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November 2018 in “Psychoneuroendocrinology” This study suggests that cerebrospinal fluid levels of the neurosteroids allopregnanolone and pregnanolone correlate negatively with PTSD and negative mood symptoms, with potential sex-specific differences in synthesis enzyme blocks.
32 citations
,
February 2014 in “Psychopharmacology” This study found that dutasteride pretreatment reduced certain sedative effects of alcohol and may decrease drinking behavior in adult men, likely by impacting neuroactive steroid levels.
6 citations
,
July 2021 in “Uro” This review discusses sexual dysfunction as a potential side effect of drugs for Benign Prostatic Hyperplasia and Lower Urinary Tract Symptoms and reports no new clinical results; it emphasizes the need for methodologically robust studies.
October 2020 in “Journal of Pharmaceutical Sciences” This study found that using gallate-containing formulations like EGCG or tannic acid increased the solubility and controlled release of finasteride in microspheres, enhancing its dermal penetration in pig skin by 10 to 50 times compared to a control.
3 citations
,
August 2018 in “Stem cells international” This study found that cultured hair follicle dermal cells support maintenance and potentially aid in the clinical application of pluripotent and haematopoietic stem cells.
January 2024 in “Wiadomości Lekarskie” This study found that using Lactobacillus reuteri DSM 17938 probiotics significantly improved IBS symptoms in children, with optimal therapy duration suggested to be 1-3 months based on symptom and calprotectin level reductions.
12 citations
,
December 2009 in “Neuroscience” GABAergic steroid precursors reduce ethanol withdrawal symptoms in certain mice.
10 citations
,
January 2017 in “Skin Pharmacology and Physiology” This case report describes a 52-year-old man who developed generalized vitiligo two months after stopping finasteride and suggests this may be part of post-finasteride syndrome.
January 2012 in “Postgraduate obstetrics & gynecology” Up to 50% of women may experience significant hair loss by age 50, with various causes and treatments available.
26 citations
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December 2019 in “Neurobiology of Stress” This review discusses adverse effects of 5 alpha-reductase inhibitors, particularly persistent side effects such as post-finasteride syndrome, and highlights the need for further investigation.
1 citations
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July 2017 in “Microbial Cell Factories” This study found that supplementing soybean oil significantly increased the production of the cyclosporine A derivative [(4'-OH)MeLeu]4-CsA by 55.6%, offering potential enhancements for its clinical application.
January 2012 in “Postgraduate obstetrics & gynecology” This descriptive abstract provides information about a continuing medical education activity for physicians, designating 1.5 credits for participation, but reports no new research findings.
48 citations
,
July 2009 in “The Journal of Sexual Medicine” In this study, 50 mg/day of DHEA supplementation in postmenopausal women did not significantly improve sexual function compared to a placebo over 26 weeks.
January 2018 in “Deleted Journal” In this observational study of 110 women with PCOS, the researchers found that 52.7% experienced depression and anxiety, with Metformin being the most prescribed drug. Regular counseling and lifestyle management were noted to improve the overall disease prognosis.
32 citations
,
July 2017 in “Clinical and Experimental Dermatology” This study assessed the use of oral finasteride in transgender men with androgenetic alopecia and found that all patients improved by one grade on the Norwood–Hamilton scale within about 5.5 months, with no significant adverse effects reported during the 16.2 months of follow-up.
April 2017 in “Reactions Weekly” Man experienced sexual dysfunction, depression, breast growth, and skin discoloration after taking finasteride for hair loss.
7 citations
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May 2013 in “Optometry and vision science” This case report observed increased eyelash growth in a trichotillomania patient using bimatoprost 0.03% solution over four months.
May 2017 in “InTech eBooks” This review discusses trichotillomania and traction alopecia, focusing on their clinical features, diagnostic criteria, and treatment options, but it reports no new research findings.
April 2015 in “Cambridge University Press eBooks” Many women experience sexual dysfunction, but few seek help, and better treatment and medical training are needed.
6 citations
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May 2017 in “InTech eBooks” This review discusses the relationship between alopecia and psychological disorders and reports no new results.
April 2025 in “Tạp chí Y Dược học Cần Thơ” This review indicates that hair loss negatively impacts psychological well-being and quality of life, highlighting the importance of comprehensive management, including psychological assessment and sleep improvement, to enhance patients’ quality of life.
January 2026 in “SKIN The Journal of Cutaneous Medicine” This systematic review found that patients with androgenetic alopecia have an elevated prevalence of psychiatric conditions, which may increase their susceptibility to post-finasteride syndrome symptoms.
January 2024 in “Wiadomości Lekarskie” This study found that in prodromal Alzheimer's disease, pro-inflammatory gut bacteria were associated with reduced cerebral blood flow and reactivity, while beneficial gut bacteria correlated with better outcomes.
January 2024 in “Wiadomości Lekarskie” In this study, a child's diagnosis of Silver-Russell syndrome was confirmed through phenotype data, genetic testing, and the exclusion of other developmental conditions, revealing a need for a multidisciplinary care approach.
January 2012 in “Anales (Reial Acadèmia de Medicina de la Comunitat Valenciana)” This study found that SRD5A2 expression is absent in one third of benign adult prostates and is associated with hypermethylation, suggesting potential personalization of treatment for prostatic diseases based on methylation status.