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Taking the same medication under different brand names caused harmful side effects.

All four treatments for early rheumatoid arthritis had similar safety profiles.

Busulfan/cyclophosphamide and total bone irradiation are equally effective for AML transplants.

Personalized thiopurine dosing based on NUDT15 genotyping can improve long-term outcomes for ulcerative colitis and Crohn's disease patients.

Propranolol is effective and safe for treating infantile hemangioma, but more research is needed for dosing and monitoring guidelines.

Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

Liposomal anthracyclines are effective and safer for treating multiple myeloma, especially in elderly patients.

Minoxidil given intravenously caused small changes in diastolic blood pressure and increased heart rate at higher concentrations in patients with high blood pressure.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

Some acne medications have side effects; doctors should educate patients and may not need to do frequent lab tests for all.

Pill organizers and cutters can help with taking medication regularly but may affect the medication's effectiveness and safety.

Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.

Chemotherapy often causes skin, nail, and hair side effects, significantly impacting quality of life.

People often struggle to consistently use contraceptives and other medications, and long-acting options might be better for those who want to avoid daily doses.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

New finasteride solution effectively reduces baldness-causing hormone, potentially with fewer side effects.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Scalp cooling is largely ineffective in preventing hair loss from breast cancer chemotherapy.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.

The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

The document concludes that gender-affirming treatments are essential for transgender individuals and outlines safe hormone therapy practices.