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Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Low-potency steroids can cause serious side effects in people with skin conditions like Netherton syndrome.

Tofacitinib helped some young children with severe hair loss grow their hair back without bad side effects.

Minoxidil can harm dog's heart.

Finasteride reduces male rat fertility by causing issues with copulatory plug formation.

Oral minoxidil helps hair growth, is cost-effective, and mostly well-tolerated.

More pediatric-specific research and guidelines are needed to improve hidradenitis suppurativa treatment in children and adolescents.

Extended-release divalproex is better tolerated and more effective for seizures and psychiatric symptoms than delayed-release divalproex, but doesn't reduce hair loss.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

Optimized film improves finasteride skin absorption and treatment efficiency.

FUE hair transplants offer minimal scarring and are good for short hairstyles but are time-consuming and can be costly.

Minoxidil may cause heart changes; use caution and monitor patients with heart conditions.

Minoxidil may help hair growth after transplant surgery.

A girl initially thought to have a psychiatric disorder was later found to have a lupus-related condition, which improved with proper treatment.

Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.

The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.

Longer contact time increases minoxidil absorption, but doesn't affect metabolism.

St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.

To stop online sexism, both men and women need to change how they act.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.

Taking oral testosterone with finasteride or dutasteride doubles testosterone levels, and food slightly affects it.

Oral minoxidil effectively treats hair loss, with women needing lower doses (0.25 to 2.5 mg daily) and men needing higher doses (1.25 to 5 mg daily).

Valproic acid and carbamazepine do not change biotin or biotinidase levels but may lower zinc levels, still within normal range.

Using longer PEG chains helps nanoparticles penetrate hair follicles better, improving drug delivery for conditions like alopecia.

Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.

Tamoxifen caused hair loss in a 52-year-old woman.

Trichotillomania is often misdiagnosed as alopecia areata and can be treated effectively with N-acetylcysteine and psychotropic drugs.