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The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

Hair graying is caused by the loss of pigment cells due to poor maintenance of stem cells in the hair follicle.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Lower melatonin levels are linked to more skin aging.

Vesicles from irradiated mouse cheek skin help cells survive radiation.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Certain nutrients can improve skin health and treat skin problems safely.

UK medical students lack dermatology education, liver biopsy patients with risk factors show more fibrosis, and certain fungi resist drugs due to melanin; genetics may influence female hair loss.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

CDK4/6 inhibitors have improved treatment outcomes for certain advanced breast cancer patients.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Voriconazole can cause serious side effects, especially in long-term use.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.

New markers and pathways have been found in skin tumors, helping better understand and diagnose them.

Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.

Melanoma development can be linked to the breakdown of skin's melanin-producing units.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

The PP2A-B55α protein is essential for brain and skin development in embryos.