research Abnormal Liver Enzymes in Thymoma-Associated Multiorgan Autoimmunity
Thymoma-associated multiorgan autoimmunity can cause liver damage and affects multiple organs, with limited treatment options and a generally poor prognosis.
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research Edematous Striae Distensae in a 14-Year-Old Girl with Nephrotic Syndrome
The girl's swelling and skin issues improved with fluid restriction and diuretics.
research Baricitinib Safety for Events of Special Interest in Populations at Risk: Analysis from Randomised Trial Data Across Rheumatologic and Dermatologic Indications
Baricitinib, a drug for rheumatoid arthritis, atopic dermatitis, and alopecia areata, is generally safe with low risk of major side effects, even in patients with risk factors. It's also effective in promoting hair regrowth in alopecia areata patients.
research Rare Presentation of Precocious Puberty Secondary to LH-Secreting Adenoma
An 8-year-old boy's early puberty was caused by a rare hormone-secreting brain tumor, which was successfully treated with surgery.
research Local Artemis Dysfunction May Be One Molecular Mechanism for Androgenetic Alopecia via Telomere Shortening
Artemis dysfunction might cause hair loss through telomere shortening.
research S1 Opioid Receptor Agonists and Serum Prostate-Specific Antigen Level: Is There a Role for Prostate Cancer Control and Chemoprevention?
Opioid use may lower PSA levels, suggesting a possible role in prostate cancer control; PSA testing is useful for detecting prostate cancer; serum triglycerides are not linked to prostate cancer risk; and higher urethral PSA levels may be associated with local hormone activity.
research A Case of Atypical Myxedema in Hypothyroidism
A woman with severe hypothyroidism had a rare skin condition usually linked to a different thyroid disease.
research Treatment of Nonclassic 11-Hydroxylase Deficiency with Hair, Skin, and Nails, an Over-the-Counter, Insulin Sensitizing Vitamin/Mineral Supplement
An over-the-counter vitamin/mineral supplement improved hair loss and blood sugar control in a woman with non-classic 11-hydroxylase deficiency.
research Study of Diffuse Alopecia in Females
Most women in the study lost hair due to stress, fever, childbirth, surgery, or thyroid issues, with low hemoglobin levels also common.
research Menkes Syndrome Presenting as Myoclonic Seizures: Neuroimaging and EEG Observations
An 11-month-old boy with Menkes disease had severe brain shrinkage and abnormal blood vessels, and didn't respond well to treatment.
research Iron-Deficiency Anemia During Childhood
Children need early diagnosis and treatment for iron-deficiency anemia to prevent learning problems and promote health.
research Evaluation of Serum Level of Zinc Alpha 2 Glycoprotein in Male Patients with Androgenetic Alopecia
Men with male pattern baldness have higher blood sugar, bad cholesterol, and ZAG protein levels than healthy men.
research Isolated DHEA-S Production by an Adrenal Neoplasm: Clinical, Biochemical, and Pathologic Findings
A rare adrenal tumor in a woman only made DHEA-S, causing hair thinning, and was removed, fixing the hormone level.
research The Case of Fever, Rash, and Positive Ehrlichia Antibodies
The woman was diagnosed with systemic lupus erythematosus (SLE) after initial misdiagnosis and improved with proper treatment.
research Severe Hyperandrogenemia and Insulin Resistance in a 12-Year-Old Girl
A 12-year-old girl with very high testosterone and insulin resistance improved with birth control pills, suggesting PCOS can cause high testosterone without tumors.
research The Optimal Indication for Testosterone Replacement Therapy in Late-Onset Hypogonadism
Testosterone replacement therapy should be used for men with low testosterone levels and symptoms of hypogonadism, after careful diagnosis and considering individual needs.
research Serum Triglyceride Concentration and Risk of Prostate Cancer: A Prospective Multicenter Study
Serum triglyceride levels are not linked to prostate cancer risk.
research Novel Presentation of a Heterozygous INSR Mutation and Markedly Elevated Testosterone Levels in a Pediatric Patient: A Case Report
A young patient with unusual insulin resistance and high testosterone levels had a rare INSR gene mutation.
research Severe Insulin Resistance in a Pediatric Patient: Key Areas to Address in Screening
The case emphasizes the need for careful screening in children for insulin resistance and related conditions.
research Secondary Amenorrhea With Absent Axillary Hair
The patient's long-term symptoms were due to Sheehan's syndrome, which improved with hormone therapy.
research Hirsutism in Young Girls: Beyond PCOS
Hirsutism in young girls can have causes other than PCOS, so diagnoses should be reassessed if treatments don't work.
research A Cellular Study of Inflammatory Responses in Women with Polycystic Ovary Syndrome: An In Vitro Model of Anti-Breast Tumor Response - A Case Control Study
Women with PCOS may have a reduced ability to fight breast tumor cells over time.
research Hirsutism: Diagnosis and Treatment
The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.
research The Risk of Coronary Heart Disease in Men with Androgenetic Alopecia
Bald men may have higher heart disease risk.
research Case Study: Hereditary Cancer Genetic Testing in Unaffected Patients May Allow for Early Intervention and Aggressive Management
Genetic testing for cancer risk can lead to early and life-saving treatments in people without symptoms.
research Hypothalamic Hamartoma with Precocious Puberty and Gelastic Seizures in a Boy: Case Report
A boy with early puberty and laughing seizures was treated, stopping seizures and slowing puberty.
research Serum Iron, Zinc, and Copper Concentration in Premature Graying of Hair
Low copper levels might cause premature graying of hair.
research Hair and Nail Manifestations of Systemic Disease
Early baldness in men may indicate risks for obesity, metabolic syndrome, insulin resistance, and heart disease, similar to women with PCOS. Alopecia areata is often linked with autoimmune diseases and mental health issues. Certain hair disorders are due to genetic issues, and chemotherapy can cause hair loss through specific biological pathways. Iron deficiency's link to hair loss is still disputed.
research Is Early Onset Androgenic Alopecia a Marker of Metabolic Syndrome and Carotid Artery Atherosclerosis in Young Indian Male Patients?
Early balding in young Indian men may indicate a higher risk of metabolic syndrome and potential heart disease.
research Novel Association of Trichothiodystrophy With Autoimmune Thyroiditis and Autoimmune Hemolytic Anemia: A Case Report
A child with trichothiodystrophy also had autoimmune thyroiditis and anemia, which is a new finding.