6 citations
,
April 2013 in “International Journal of Dermatology” This correspondence article discusses a case of androgenetic alopecia treated with valproic acid but does not present new clinical findings.
1 citations
,
April 2002 in “PubMed” This case report documents a young woman who experienced a visual field defect similar to those linked to vigabatrin use, despite treatment only with valproic acid and carbamazepine, suggestive of a possible metabolic vulnerability in certain patients with specific genetic backgrounds.
13 citations
,
January 2007 in “Epilepsia” This case report describes a 47-year-old woman who experienced reversible curling of her hair during treatment with valproic acid, suggesting potential side effects on hair texture.
17 citations
,
January 2013 in “Indian Journal of Pharmacology” This case report highlights an interest in exploring the relationship between serum levels of sodium valproate and hair loss, though no case reports currently establish this link.
5 citations
,
November 2012 in “Journal of Clinical Psychopharmacology” This case report describes an 80-year-old man who developed valproate toxicity and functional decline after starting isoniazid, highlighting a potential drug interaction in elderly patients.
October 2024 in “Frontiers in Pharmacology” This study found that in patients with genetic generalized epilepsies, certain gene variants were linked to differences in valproic acid treatment outcomes, including a higher likelihood of treatment failure, varying serum drug concentrations, and specific side effects like weight gain and hair loss.
March 2019 in “Reactions Weekly” May 2021 in “American journal of medical sciences and medicine” This study observed that vomiting was the most frequent side effect of sodium valproate in children under two years old, with anemia, hair loss, and appetite loss being less common.
In this study, Convulsofin was effective as monotherapy for generalized primary epilepsy and as adjunctive treatment for therapy-resistant secondary and partial epilepsy, though side effects like gastrointestinal issues and weight gain were noted.
2 citations
,
June 1986 in “Journal of Clinical Pharmacy and Therapeutics” This study demonstrated that certain metal salts can bind to sodium valproate and discussed the potential link to hair loss in patients treated for epilepsy.
46 citations
,
December 2014 in “Epilepsy & behavior” This study found that weight gain and alopecia were the most common cosmetic side effects of AEDs, with valproic acid and pregabalin being particularly associated with these effects.
3 citations
,
November 2019 in “Clinical psychopharmacology and neuroscience/Clinical Psychopharmacology and Neuroscience” Valproate can cause both hair loss and curly hair in bipolar disorder patients.
105 citations
,
August 2010 in “Pharmacology & therapeutics” This article explores the potential of formyl-peptide receptor 2 agonists as innovative anti-inflammatory drugs, highlighting their ability to mimic the body's natural inflammation response, but it presents no new clinical findings.
85 citations
,
April 2007 in “Dermatologic Clinics” This article reviews drug-induced hair changes, highlighting that while many drugs are occasionally linked to hair loss, this connection has been conclusively established for only a few, and such hair loss is typically reversible.
65 citations
,
July 2013 in “International Clinical Psychopharmacology” This review provides an overview of the prevalence and management of side effects of mood-stabilizing drugs in bipolar disorder patients and reports no new clinical results.
47 citations
,
March 2019 in “Journal of immunology research” This review discusses the effects of valproic acid on immune cell activation and gene expression, potentially influencing infection outcomes and suggesting its promise for autoimmune and hypersensitivity condition management.
40 citations
,
August 2006 in “Current Drug Safety” This article reviews how various drugs may cause hair loss, stimulate growth, or alter hair characteristics, but reports no new clinical results; drug-induced hair loss is typically reversible.
31 citations
,
October 2013 in “Psychosomatics” This review discusses cutaneous adverse effects of psychotropic medications and reports no new findings, emphasizing the importance of psychiatrists being aware of these potential skin reactions.
22 citations
,
November 2014 in “Psychiatric Clinics of North America” This article reviews stress-related skin reactions, psychodermatology, and neuropsychiatric skin manifestations, and reports no new clinical results.
19 citations
,
October 2013 in “Headache: The Journal of Head and Face Pain” This review discusses conventional and alternative treatments for trigeminal autonomic cephalalgias, including cluster headache, paroxysmal hemicrania, and SUNCT, and recommends specific medications without reporting new clinical findings.
15 citations
,
October 2006 in “Journal of the American Academy of Dermatology” This case report describes subcutaneous emphysema in a patient's forearm as a rare complication of liquid nitrogen spray used on hypertrophic actinic keratosis, resolving spontaneously within a day.
13 citations
,
October 2010 in “Pharmacogenomics” This study constructed a panel of pharmacokinetic and pharmacodynamic genes, revealing that current SNP chips insufficiently capture many drug-response gene variants, highlighting the need for complementary genetic approaches.
6 citations
,
October 2013 in “Expert Review of Dermatology” This review explores how psychotropic medications can cause a range of skin reactions, from mild to life-threatening, and emphasizes the importance of monitoring for these adverse effects early in treatment.
5 citations
,
January 2021 in “Journal of Cosmetic Dermatology” This study found that topical cetirizine treatment significantly improved hair regrowth and patient satisfaction in male patients with androgenetic alopecia compared to a placebo, highlighting its potential role in treatment.
5 citations
,
February 2010 in “Expert Review of Dermatology” This article reviews the interconnectedness of the skin and nervous system and discusses various treatment options for psychophysiological skin disorders, reporting no new clinical results.
4 citations
,
August 2001 in “Epilepsia” This narrative review discusses issues in the treatment of epilepsy, focusing on antiepileptic drug compliance, side effects, and the challenges of drug selection; it reports no new clinical findings.
2 citations
,
January 2019 in “Elsevier eBooks” This review discusses biotin's role in nutrition and suggests no benefit to supplementing it for hair, nails, and skin in healthy individuals; it reports preliminary findings that high dosages may help some multiple sclerosis patients.
1 citations
,
January 2013 in “Springer eBooks” The document concludes that skin and nail changes can indicate various underlying health conditions.
June 2026 in “International Journal of Drug Delivery Technology” In this study, researchers developed a polyherbal hair growth oil using botanical substances and base oils like coconut and castor oil, finding it to be stable, non-irritating, and suggesting potential hair-growing properties through mechanisms such as scalp blood flow improvement and anti-inflammatory effects.
April 2026 in “Frontiers in Pharmacology” This study revealed significant signals of drug-related cognitive disorders in several medications that lack relevant FDA label warnings, suggesting a need for increased clinical awareness and potential label updates.