138 citations,
November 2015 in “Journal of Pharmacology and Experimental Therapeutics” Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.
90 citations,
May 1972 in “Clinical Pharmacology & Therapeutics” Minoxidil quickly leaves blood, turns into urine metabolites, and has lasting blood pressure-lowering effects.
75 citations,
January 2014 in “Archiv Der Pharmazie” Jasmonic acid and its derivatives play important roles in plant health and have potential uses in medicine and agriculture.
37 citations,
May 1999 in “Australasian Journal of Dermatology” Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.
30 citations,
April 1997 in “European journal of endocrinology” The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.
28 citations,
August 2011 in “Journal of The American Academy of Dermatology” Early hair loss may indicate prostate issues.
27 citations,
June 2015 in “Journal of photochemistry and photobiology. B, Biology” The new lab-grown skin model is good for testing sunscreen's protection against DNA damage from UV light.
18 citations,
January 2013 in “Postepy Dermatologii I Alergologii” Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.
18 citations,
April 2011 in “International Journal of Molecular Medicine” Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.
15 citations,
January 1988 in “Drugs” The document concludes that treatments for female hair loss and excessive hair growth are temporary and not well-studied.
14 citations,
May 2019 in “Experimental Dermatology” Fat tissue extract may help treat vitiligo by reducing cell stress and promoting skin repair.
12 citations,
January 1991 in “Archives of dermatological research” Male hormones control a specific gene in hamster skin, with different hormones having varying effects.
12 citations,
July 1957 in “Journal of Investigative Dermatology” Giving dihydrotachysterol to mother rats caused skin hardening and bone issues in their babies through milk.
11 citations,
March 2016 in “Translational Andrology and Urology” Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.
9 citations,
January 2019 in “American Journal of Dermatopathology” DKK-1 gene linked to hair loss in AGA and AA patients; more research needed for potential therapy.
8 citations,
October 2008 in “Medical hypotheses” Baldness might be caused by scalp weight pressing on hair follicles.
7 citations,
July 2005 in “Journal of Dermatological Science” The gene URB is more active in human hair growth cells and responds to a hair-related hormone.
6 citations,
August 2017 in “Physiological Research” Setipiprant may reduce inflammation by blocking an enzyme called aldose reductase.
5 citations,
April 2021 in “Journal of Endocrinological Investigation” Higher DHT levels are linked to fewer hypogonadism symptoms in men with normal testosterone levels.
5 citations,
December 1979 in “Clinical and Experimental Dermatology” Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.
2 citations,
January 2020 in “International Journal of Cosmetic Science” Niacinamide does not promote hair growth.
1 citations,
May 2013 in “Journal of the Egyptian Women's Dermatologic Society (Print)” Women with hair loss have higher heart disease risk and unhealthy cholesterol levels.
June 2017 in “Journal of The American Academy of Dermatology” Teriflunomide often causes mild to moderate hair thinning and loss in MS patients, which usually improves with or without treatment.
June 2017 in “Journal of The American Academy of Dermatology” Tapinarof cream at 1% concentration is effective and better tolerated for treating atopic dermatitis than the 2% concentration.
May 2017 in “Journal of The American Academy of Dermatology” An intact skin barrier is crucial to prevent infection in cases of tether-induced tenosynovitis.
May 2017 in “Journal of The American Academy of Dermatology” 595 nm pulsed dye laser is a cost-effective treatment for nonmelanoma skin cancer with a low recurrence rate.
May 2003 in “Facial Plastic Surgery Clinics of North America” Hair loss can be treated with medications like minoxidil and finasteride or surgery, but treatment effectiveness varies by alopecia type and accurate diagnosis is important.
February 2020 in “Bulletin of Experimental Biology and Medicine” Finasteride and GIZh-72 reduce inflammation, with GIZh-72 being more effective.
January 2015 in “Ankara Üniversitesi Tıp Fakültesi mecmuası” Men with severe hair loss may have a higher risk of heart disease.
129 citations,
October 2000 in “British Journal of Dermatology” Finasteride helps increase hair growth in men with hair loss.