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      Spatiotemporal Control of CRISPR/Cas9 Gene Editing

      research Spatiotemporal control of CRISPR/Cas9 gene editing

      51 citations , June 2021 in “Signal Transduction and Targeted Therapy”
      This review article summarizes recent strategies to enhance the precise control of CRISPR/Cas9 gene editing, addressing tissue-specific challenges and off-target effects by exploring various activation methods like cell-specific promoters and small molecules.
      Advances in the Management of Alopecia Areata

      research Advances in the management of alopecia areata

      51 citations , December 2011 in “The Journal of Dermatology”
      This review discusses updated treatment guidelines for alopecia areata in Japan, highlighting new options like corticosteroid pulse therapy, but reports no new clinical results.
      Polycystic Ovary Syndrome: Early Detection in Adolescents

      research Polycystic Ovary Syndrome: Early Detection in the Adolescent

      50 citations , February 2007 in “Clinical obstetrics and gynecology”
      This review discusses the clinical manifestations and diagnostic challenges of polycystic ovary syndrome in adolescents, emphasizing the importance of early diagnosis and intervention to manage symptoms effectively, but it reports no new clinical results.
      Alopecia Areata: Clinical Review and Treatment Approaches

      research Alopecia Areata

      50 citations , March 2000 in “American Journal of Clinical Dermatology”
      This article discusses the etiology, clinical features, and treatment of alopecia areata but presents no new clinical findings, underlining the palliative nature of current therapies.
      An Approach to the Patient with Hirsutism

      research An Approach to the Patient with Hirsutism

      49 citations , September 2012 in “˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”
      This review discusses the physiology of hair growth, common abnormal patterns of hirsutism, and examines differential diagnoses and treatment options, but provides no new clinical findings.
      Nonclassic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency: Pathophysiology, Diagnosis, and Treatment

      research Nonclassic Congenital Adrenal Hyperplasia

      49 citations , January 2010 in “International Journal of Pediatric Endocrinology”
      This review covers the pathophysiology, diagnosis, and treatment of nonclassic congenital adrenal hyperplasia due to P450c21, but it reports no new clinical results.
      Alopecia Secondary to Mesotherapy

      research Alopecia secondary to mesotherapy

      49 citations , July 2009 in “Journal of the American Academy of Dermatology”
      This report highlights two cases where patchy alopecia developed after mesotherapy for androgenetic alopecia, indicating potential risks associated with this treatment.
      The Pharmacologic Treatment of Muscle Pain

      research The Pharmacologic Treatment of Muscle Pain

      49 citations , July 2004 in “Anesthesiology”
      This review discusses pharmacologic treatment options for muscle-related pain conditions and notes that there is strong evidence for the efficacy of tricyclic antidepressants and muscle relaxants in specific myofascial pain syndromes, but not universally.
      Alopecia Areata: A Review of Treatments and Their Efficacy

      research Alopecia Areata

      49 citations , November 1992 in “Archives of dermatology”
      This article discusses the emotional and psychological impact of severe alopecia areata on patients, emphasizing feelings of loss, vulnerability, and self-identity changes, and reports no new results.
      Primary Generalized Glucocorticoid Resistance And Hypersensitivity

      research Primary Generalized Glucocorticoid Resistance and Hypersensitivity

      48 citations , January 2011 in “Hormone Research in Paediatrics”
      This review discusses the molecular basis and clinical implications of primary generalized glucocorticoid resistance and hypersensitivity, attributing them to mutations in the human glucocorticoid receptor gene, and reports no new clinical findings.
      Microneedle-Based Approaches for Skin Disease Treatment

      research Microneedle-Based Approaches for Skin Disease Treatment

      48 citations , February 2025 in “Nano-Micro Letters”
      This review summarizes the application of microneedles in treating various skin diseases and highlights challenges like low drug loading, noting no new clinical results are reported.
      Alopecia With Endocrine Therapies in Patients With Cancer

      research Alopecia With Endocrine Therapies in Patients With Cancer

      48 citations , September 2013 in “Oncologist”
      This study reported that alopecia is a common but often underreported side effect of endocrine-based cancer therapies, with tamoxifen showing the highest incidence of hair loss among analyzed treatments.
      Polycystic Ovary Syndrome: A Common But Often Unrecognized Condition

      research Polycystic Ovary Syndrome: A Common But Often Unrecognized Condition

      48 citations , May 2012 in “Journal of Midwifery & Women's Health”
      This review discusses the symptoms, diagnosis, and current treatment recommendations for polycystic ovary syndrome, noting that many women may remain undiagnosed and at risk for complications.
      Toxic Epidermal Necrolysis

      research TOXIC EPIDERMAL NECROLYSIS

      48 citations , November 1992 in “International Journal of Dermatology”
      This article discusses the history and terminology of toxic epidermal necrolysis but reports no new clinical results.
      Idiopathic Hirsutism: Androgen Role and Treatment Options

      research Idiopathic Hirsutism*

      47 citations , August 2000 in “Endocrine Reviews”
      This review discusses idiopathic hirsutism, potential underlying mechanisms, and various therapeutic approaches without providing new clinical results, and emphasizes the need for further research on well-defined patient groups.
      Skin Steroidogenesis in Health and Disease

      research Skin steroidogenesis in health and disease

      47 citations , September 2016 in “Reviews in endocrine and metabolic disorders”
      This review discusses the steroidogenic properties of human skin and suggests that impaired steroidogenesis may be linked to conditions like acne, rosacea, atopic dermatitis, and androgenic alopecia, but reports no new clinical results.
      Chrousos Syndrome: From Molecular Pathogenesis to Therapeutic Management

      research Chrousos syndrome: from molecular pathogenesis to therapeutic management

      47 citations , February 2015 in “European Journal of Clinical Investigation”
      This review discusses Chrousos syndrome, a rare condition caused by NR 3C1 gene mutations leading to glucocorticoid resistance, and reports no new clinical results; early identification and genetic testing are recommended for diagnosis.
      The Skin in Pregnancy: A Review of Normal Changes

      research The Skin in Pregnancy

      47 citations , May 2002 in “Journal of Cutaneous Medicine and Surgery”
      This review discusses normal skin changes during pregnancy such as pigmentary and glandular alterations, highlighting the need for physician awareness to avoid unnecessary treatments, and reports no new clinical findings.
      A Review on Traditional Uses, Phytochemistry, and Pharmacology of Eclipta Prostrata (L.) L.

      research A review on traditional uses, phytochemistry and pharmacology of Eclipta prostrata (L.) L.

      46 citations , August 2019 in “Journal of Ethnopharmacology”
      This review compiles current information about Eclipta prostrata, traditional uses, and its promising pharmacological properties, like hepatoprotective and anti-inflammatory effects, but emphasizes that more research is needed to fully understand its mechanisms and ensure safety for clinical application.
      Hair and Scalp Changes in Cutaneous and Systemic Lupus Erythematosus

      research Hair and Scalp Changes in Cutaneous and Systemic Lupus Erythematosus

      46 citations , June 2018 in “American Journal of Clinical Dermatology”
      This review summarizes the clinical, trichoscopic, and histopathological features of alopecia types associated with cutaneous and systemic lupus erythematosus and explores their links to disease activity, but it reports no new clinical results.
      Hormonal Treatment of Acne Vulgaris: An Update

      research Hormonal treatment of acne vulgaris: an update

      46 citations , September 2016 in “Clinical, Cosmetic and Investigational Dermatology”
      This article reviews the hormonal pathogenesis and treatment strategies for acne vulgaris, particularly in women with severe or treatment-resistant cases, associating it with hormonal imbalances and hyperandrogenism.