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Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

A man with a rare scalp cancer was successfully treated, highlighting the need for early management to prevent spread and complications.

Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.

Permanent hair loss after bone marrow transplant can be caused by chemotherapy or chronic graft-versus-host disease.

Chemotherapy and bone marrow transplant can cause permanent hair loss.

Ishige sinicola extract helps bone-building cells grow and mature, which could aid in treating osteoporosis.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Testosterone replacement therapy improves libido, mood, muscle strength, and bone density in men with Testosterone Deficiency Syndrome.

Deoxyshikonin helps wounds heal faster in diabetic mice.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Higher early lead exposure is linked to delayed puberty in girls.

Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Finasteride effectively treats baldness but may cause sexual side effects.

Activin B improves wound healing and hair growth by helping stem cells move using certain cell signals.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

DHT inhibition may increase spinal bone growth in ankylosing spondylitis.

5-Alpha reductase inhibitors may prevent prostate cancer but are not widely used due to concerns about trial relevance and potential risks, and more research is needed to confirm long-term benefits.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

Too much zinc in the diet can cause hair loss and color change in young mice by reducing copper in the body.

Satoyoshi syndrome is likely an autoimmune disease that mainly affects young women and improves with immune-related treatments.

Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

A patient with Werner syndrome showed a range of aging-like symptoms and metabolic issues, underscoring the need for early detection and treatment.

The article concludes that cranial reconstruction should aim for the best aesthetic result, using various techniques tailored to individual needs and conditions.

New treatments are making advanced prostate cancer management more complex but also more hopeful.