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Minoxidil effectively treats severe hypertension but has notable side effects.

A woman with HIV had a severe skin condition that improved with antiretroviral therapy.

HIV-infected men who have sex with men are at higher risk for aggressive syphilis, but treatment and tests are effective.

The document concludes that autoimmune skin disorders are treated with corticosteroids and immunosuppressive drugs.

The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Three new types of a skin blistering disease were found, caused by specific gene mutations.

Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.

Mice can regenerate ear tissue without the p53 protein.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

Combining skin tissue pathology with genetics has greatly improved the diagnosis and understanding of certain skin diseases.

A five-month-old boy with Omenn syndrome successfully recovered after a stem cell transplant with reduced intensity conditioning.

BMP4-related anomalies can cause a wide range of eye, brain, and hand/foot problems, and new cases show this variability.

Rapamycin may help treat Leigh syndrome by targeting protein kinase C.

Minoxidil does not work to inhibit lysyl hydroxylases in newborn mouse lungs.

Newborn screening and gene therapy are expected to improve outcomes for Omenn syndrome patients.

The document concludes that finasteride can reduce nandrolone detection in doping tests, suggesting frequent testing and setting metabolite level thresholds for detection.

The study found that tight junctions reach the top layer of the skin's stratum granulosum, not just the second top layer as previously thought.

Follicle Stimulating Hormone is important for fertility.

Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.

Certain gene mutations can weaken the skin barrier and, when combined with environmental factors, lead to eczema and severe itching.

Skin symptoms are important for diagnosing infections in children.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.