research Pegylated Liposomal Doxorubicin: Metamorphosis of an Old Drug into a New Form of Chemotherapy
Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.
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research Mechanisms and Applications of the Anti-Inflammatory Effects of Photobiomodulation
Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.
research Modulating the Stem Cell Niche for Tissue Regeneration
Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
research Molecular Principles of Hair Follicle Induction and Morphogenesis
Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
research Proteasome Inhibitors: An Expanding Army Attacking a Unique Target
Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.
research The Polycystic Ovary Syndrome: A Position Statement from the European Society of Endocrinology
The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.
research Rosacea: Etiology, Pathogenesis, And Subtype Classification
Rosacea is a skin condition with unclear causes, classified into four subtypes.
research Alopecia Areata: An Autoimmune Disease Causing Hair Loss
Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
research Colon Cancer Stem Cells: Promise of Targeted Therapy
Targeting colon cancer stem cells might lead to better treatment results.
research Regeneration of Fat Cells from Myofibroblasts During Wound Healing
Some wound-healing cells can turn into fat cells around new hair growth in mice.
research Skin Melanocytes: Biology and Development
The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.
research Alopecia Areata Update
Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.
research Improving Human Forensics Through Advances in Genetics, Genomics, and Molecular Biology
DNA profiling in forensics has improved, but predicting physical traits and ancestry from DNA has limitations and requires ethical consideration.
research Neuroimmunology of Stress: Skin Takes Center Stage
Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.
research Complications of Cushing's Syndrome: State of the Art
Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.
research Treatment of Hair Loss
Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.
research Wound Healing and Skin Regeneration
Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
research Treatment of Invasive Aspergillosis with Itraconazole
Itraconazole is potentially effective for treating invasive aspergillosis, but more research is needed.
research The Cutaneous Serotoninergic/Melatoninergic System: Securing a Place Under the Sun
Human skin can make serotonin and melatonin, which help protect and maintain it.
research Evidence-Based and Potential Benefits of Metformin in Polycystic Ovary Syndrome: A Comprehensive Review
Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
research Calreticulin: Non-Endoplasmic Reticulum Functions in Physiology and Disease
Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.
research Stem Cells and the Niche: A Dynamic Duo
Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
research Mesenchymal Stromal Cell Secretome: Influencing Therapeutic Potential by Cellular Pre-Conditioning
Changing how mesenchymal stromal cells are grown can improve their healing abilities.
research Regulation of Somatic Cell Reprogramming Through Inducible miR-302 Expression
Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.
research The Dynamics of the Skin’s Immune System
The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
research Recent Understandings of Biology, Prophylaxis, and Treatment Strategies for Hypertrophic Scars and Keloids
The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.
research Bioactivities, Isolation and Purification Methods of Polysaccharides from Natural Products: A Review
Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.
research Single-Cell Analysis Reveals Fibroblast Heterogeneity and Myeloid-Derived Adipocyte Progenitors in Murine Skin Wounds
The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.
research Fibroblast Heterogeneity: Implications for Human Disease
Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition
The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.