January 2026 in “Supportive Care in Cancer” This narrative systematic review reports that gel-based, cryogel, and silicone-based cooling caps offer cost-effective and environmentally sustainable alternatives to traditional machine-operated systems for preventing chemotherapy-induced hair loss, particularly benefiting low-income and low-resource settings.
7 citations
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December 2015 in “Journal of thermal biology” This study used numerical models to explore the cooling power required by different scalp cooling devices to prevent chemotherapy-induced hair loss, finding that coolant temperature significantly influences scalp tissue temperatures.
39 citations
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January 1994 in “European Journal of Cancer” In this study, scalp hypothermia with the Theracool™ cooling machine was largely ineffective for preventing alopecia in breast cancer patients undergoing a chemotherapeutic regimen including cyclophosphamide and anthracyclines.
62 citations
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February 2011 in “Expert review of dermatology” This review discusses the incidence, reversibility, and impact of chemotherapy-induced alopecia and concludes that scalp cooling is the most effective prevention method in most cases, though some questions remain.
38 citations
,
September 2017 in “Oncologist” This source reports that scalp cooling is currently the only safe and FDA-cleared method to potentially reduce chemotherapy-induced hair loss, with about a 50% chance of maintaining sufficient hair to avoid needing a wig.
3 citations
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January 2011 in “Wspolczesna Onkologia-Contemporary Oncology” Scalp hypothermia can prevent chemotherapy-induced hair loss but is not suitable for all patients, and more research is needed to improve prevention methods.
August 2018 in “SDÜ SAĞLIK BİLİMLERİ DERGİSİ” In this review, the authors examine the causes, risk factors, and management strategies for chemotherapy-induced hair loss, highlighting its psychological impact and underscoring the role of healthcare providers, especially nurses, in supporting patients through this distressing side effect.
17 citations
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June 2020 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This paper provides an overview of scalp cooling as an effective and safe intervention for preventing chemotherapy-induced alopecia, addressing its impact on cancer patients and survivors.
19 citations
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January 2023 in “ACS Omega” This study developed sodium alginate and epigallocatechin gallate cryogels cross-linked with ferric ions, showing that they have strong antibacterial properties and rapid hemostatic abilities, making them promising candidates for wound dressing applications.
37 citations
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October 2017 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This literature review reported that scalp hypothermia significantly decreases the occurrence of chemotherapy-induced alopecia, increasing effectiveness by 2.7-fold in controlled clinical trials and 3.9-fold in randomized trials, and highlighted a need for standard guidelines for its use.
June 2006 in “The American Journal of Cosmetic Surgery” Advancements in cosmetic and reconstructive surgery improve techniques and patient satisfaction.
159 citations
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September 2001 in “European Journal of Cancer Care” This literature study reviews the consequences of hair loss due to chemotherapy and nursing care interventions but reports no new clinical results.
37 citations
,
December 2024 in “Theranostics” In this study, a newly developed nanoparticle-loaded hydrogel wound dressing demonstrated significant antibacterial, antioxidant, anti-inflammatory, and proangiogenic activities, effectively reducing pain and promoting healing in a murine burn wound model while preventing infection by *Staphylococcus aureus*.
6 citations
,
April 2012 in “Lasers in surgery and medicine” This study observed that persistent urticaria is a rare side effect of laser epilation, potentially linked to a hypersensitivity reaction in patients with allergies.
11 citations
,
September 2023 in “ACS Omega” This review highlights the rapid advancements in 3D bioprinting techniques, emphasizing their role in enhancing regenerative therapy, drug delivery, and bioengineering applications while addressing current challenges in bioink formulation and bioprinting stability.
15 citations
,
June 2023 in “Molecules” This study focused on developing agarose/fucoidan hydrogels for the encapsulation of pancreatic cells, reporting that these materials supported cell viability and self-organization into pseudo-islets over 7 days, highlighting potential for diabetes treatment applications.
4 citations
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September 2025 in “Pharmaceutics” This review highlights the potential of natural hydrogels as advanced wound dressings, emphasizing their capabilities in mimicking the extracellular matrix, supporting healing, and delivering therapeutic agents for chronic and infected wound care.
January 2024 in “Dermatologic Surgery” This abstract pertains to a dermatology-related academic profile without reporting any specific study findings. Results or research details are not provided.
53 citations
,
June 1982 in “The BMJ” Cooling the scalp below 22°C before and during chemotherapy can help prevent hair loss.
92 citations
,
January 1999 in “Physics in Medicine and Biology” This study developed and validated a computational model to optimize skin precooling methods for minimizing thermal damage during laser procedures.
December 2025 in “Journal of Pharma Insights and Research.” This paper reviews the state of knowledge on injectable cryogels, highlighting their unique properties such as shape-memory and mechanical integrity, which allow for minimally invasive delivery via needles and potential applications in oncology and regenerative medicine.
November 2025 in “Bioactive Materials” In this study, researchers developed a DNA/GelMA-based cryogel platform that uses phototherapy to combat MRSA infection and promote scarless wound healing, showing enhanced bactericidal activity, tissue regeneration, and anti-inflammatory effects in vivo, suggesting a promising approach for treating infected skin wounds.
3 citations
,
March 2008 in “Medical laser application” This review highlights recent advances in laser treatments for skin disorders, including the optimization of vascular lesion treatment and improved safety for hair removal, but reports no new results.
150 citations
,
April 1999 in “Dermatologic Clinics” This article reviews the biological and physical principles of laser hair removal and reports that current laser systems do not consistently achieve permanent hair follicle destruction across treated areas.
73 citations
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April 1999 in “Dermatologic Clinics” This article reviews patient selection and treatment protocols for various light-based hair removal systems but presents no new clinical results.
15 citations
,
January 2003 in “Lasers in Surgery and Medicine” This study found that cold air can effectively preserve the epidermis when using an 810 nm diode laser, but it is slightly less effective than a chilled sapphire window in dark-haired pigmented pigs.
27 citations
,
July 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” This narrative review discusses the evolution and diverse medical applications of laser technologies, particularly in dermatology and skin biology, without reporting new research findings.
January 2018 in “Springer eBooks” This review discusses the factors affecting laser hair removal results and adverse events, emphasizing the need for more research to determine optimal treatment parameters; it reports no new clinical findings.
March 2024 in “Asian journal of medical sciences” In this study, researchers found that a ring block technique was the most accepted anesthesia modality for platelet-rich plasma injections in hair loss treatment, with the least post-procedural pain compared to other methods like vibration anesthesia and nerve blocks.
39 citations
,
June 1982 in “The BMJ” Blood tests confirmed a baby in the womb had a CMV infection.