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Long-term use of certain prostate drugs can worsen erectile dysfunction by changing penile tissue, especially in rats with high blood pressure.

SHH protein helps nerve regeneration in hypertensive rats.

Dutasteride caused more penile tissue changes than finasteride, possibly increasing erectile dysfunction risk.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

Finasteride changes hormone levels and certain proteins in rats, but these effects can be reversed after stopping the drug.

5-alpha-reductase inhibitors significantly affect the penile tissue of hypertensive rats.

More hair loss leads to higher risk of psychosexual disorders, especially in women.

Future hormone therapy trials should match the diverse needs and priorities of the gender-diverse community.

Non-infectious skin conditions are more common than infectious ones in Kashmir, but community areas see more infections, suggesting a need for better skin care services in primary health care.

Skin infections and eczema were most common in all ages, acne in teens and young adults, and nutritional skin problems and infestations in children.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The document explains hair and nail biology, common hair loss conditions and treatments, oral and genital skin diseases, and the risks and treatments associated with squamous cell carcinoma.

Measuring the distance from the anus to the clitoris may moderately help diagnose polycystic ovary syndrome, especially in certain cases.

Hormones significantly affect women's sexual function, and more research is needed to improve treatments for sexual dysfunction with minimal side effects.

Longer anogenital distance may indicate a higher chance of having polycystic ovary syndrome, and measuring this distance along with hormone levels could improve diagnosis.

Patients should consult urologists for evidence-based erectile dysfunction treatments.

Finasteride may be linked to Peyronie’s disease, but more research is needed.

More research is needed on the health effects of hormone therapy for transgender and nonbinary people.

Stem cell treatment improved life quality and sexual function in women with hair loss.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Pubertal acne is linked to hormonal changes, affects quality of life, and is treated similarly to adult acne.

Dermoscopy is a useful tool for identifying features of skin conditions, but more research is needed to define its role in dermatology.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The 2018 update to the ED care model added a new severity score and stressed a detailed evaluation of both physical and psychological aspects.

Delayed ejaculation is a complex issue caused by psychological, biological, and lifestyle factors, requiring a holistic treatment approach.

Healthcare providers need better education and policies to serve transgender individuals effectively.