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Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

South Asian women with PCOS experience more psychological distress and have a poorer quality of life, especially in social relationships, with hirsutism affecting them more than obesity.

Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.

Early detection and treatment of PCOS in teenagers is important to manage symptoms and prevent severe issues.

Genes and hormones cause hair loss, with four genes contributing equally.

Alopecia Areata has no guaranteed treatment for hair regrowth, but options like corticosteroids and minoxidil are used, with future research focusing on genetic and immune therapies.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

Psoriasis is linked to other autoimmune diseases and involves a specific inflammatory process.

Hair loss links to higher death risk from diabetes and heart disease; not a direct cause, but a marker for risk factors.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

The document concludes that more research is needed to understand how to treat muscle pain with drugs.

Higher IGF-1 levels in hair follicles link to better finasteride results for hair loss.

Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.

A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.

People with alopecia are at higher risk for heart disease and have more heart-related risk factors.

Women with PCOS often have hair loss, which is linked to acne or excess body hair but not to worse hormone or metabolic issues.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

Hair growth is controlled by specific gene clusters and proteins, and cysteine affects hair gene expression in sheep.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

HIV can cause various nail and hair disorders, important for early diagnosis and treatment.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.