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Lipid nanoparticles improve drug delivery through the skin, offering stability, controlled release, and better compatibility with skin.

Single-cell engineered biotherapeutics show promise for skin treatment but need more research and trials.

Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.

Proper hair care and safe use of hair products are crucial for those with hair loss.

Goat skin changes with the seasons due to genes affected by daylight and hormones.

Silk proteins are great for cosmetics because they protect and improve skin and hair while being eco-friendly.

Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.

Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.

Higher TGF-β signaling may increase skin cancer risk in organ transplant recipients.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.

Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.

Water and fatty acids affect hair's surface differently based on hair damage, and models can help understand hair-cosmetic interactions.

Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Polymeric nanoparticles show promise for treating skin diseases.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.