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The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Androgens can both increase and decrease hair growth in different parts of the body.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Researchers created human hair follicles using a new method that could help treat hair loss.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Androgens can cause hair growth in some areas and hair loss on the scalp.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

Peptide hydrogels heal burn wounds faster and better than standard dressings.

Estrogen therapy can reduce skin aging but has cancer risks.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Finasteride effectively blocks enzyme causing male pattern baldness.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.