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The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

Manage vitiligo with treatments, address emotions, and use camouflage techniques.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

Low iron levels may be linked to some types of hair loss in women.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Humans lost body hair relatively recently in evolution.

Stem cell self-renewal is complex and needs more research for full understanding.

Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Hair loss linked to higher heart disease risk in both men and women.

Finasteride with oral contraceptive helps improve hair loss in premenopausal women.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.

Finasteride may cause slight depression and anxiety.

No treatment fully prevents hair loss from chemotherapy yet.