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5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

Alopecia Areata is an autoimmune condition often starting before age 20, with varied treatment success and a need for personalized treatment plans.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

New methods have greatly improved our understanding of stem cell behavior and roles in the body.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.

Lasers and light sources can effectively remove hair, work best on fair skin with dark hair, and usually need multiple treatments.

Minoxidil and finasteride treat hair loss; more research needed for other options.

Alopecia areata can cause unpredictable hair loss, and treatments like corticosteroids and minoxidil may help but have varying side effects.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Vitamin D3 affects cell differentiation in specific skin areas.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Cancer development is like natural selection, involving mutated cells and environmental factors.

Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Both mouse and rat models are effective for testing alopecia areata treatments.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

Melatonin affects mouse skin and may regulate skin functions.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.