119 citations,
November 2014 in “Trends in Cell Biology” Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.
8 citations,
October 2016 in “Experimental dermatology” Hair follicles may help teach the immune system to tolerate new self-antigens, but this can sometimes cause hair loss.
54 citations,
May 1998 in “Urology” Men with enlarged prostates often have more severe baldness.
24 citations,
October 2017 in “Biomolecules” Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
18 citations,
November 2012 in “Current opinion in urology” Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.
87 citations,
September 2014 in “International Journal of Molecular Sciences” FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.
39 citations,
May 2014 in “Frontiers in Pharmacology” Special immune cells called Tregs can help prevent lung scarring by blocking a specific growth factor.
4 citations,
January 2023 in “Journal of Human Hypertension” Women experience more side effects and have worse blood pressure control from hypertension treatments than men, despite using different medications.
53 citations,
October 1984 in “Endocrine reviews” Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
88 citations,
August 2019 in “Frontiers in immunology” Tyrosine kinases are important in skin autoimmune diseases and could be targets for new treatments.
107 citations,
August 2012 in “Seminars in Cell & Developmental Biology” The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
18 citations,
December 2006 in “Clinical dysmorphology” A 2-year-old boy with a rare brain malformation may have Gomez–López-Hernández syndrome.
179 citations,
May 1982 in “The Journal of clinical investigation/The journal of clinical investigation” High levels of 3 alpha-diol glucuronide in the blood are a marker of increased androgen action in women with excessive hair growth of unknown cause.
19 citations,
August 2016 in “Health and Quality of Life Outcomes” Metformin helped improve the quality of life for Chinese women with PCOS, especially in physical health and symptoms like infertility, acne, and hair loss.
32 citations,
January 2017 in “Orphanet journal of rare diseases” FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.
271 citations,
May 2019 in “Cells” The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.
19 citations,
February 2017 in “Journal of radiation research” High-dose radiation speeds up aging in skin stem cells.
2 citations,
December 2020 in “Phytomedicine plus” Taking Saw palmetto and Pygeum africana can change the levels of certain steroids in urine, which could cause confusion in doping tests.
March 2024 in “Antioxidants” Excessive blue light harms eye cells and disrupts sleep patterns.
4 citations,
May 2024 in “The Lancet” Bariatric surgery improves ovulation rates in women with PCOS and obesity better than medical therapy.
February 2020 in “Research Square (Research Square)” Women with PCOS have worse physical health but similar mental health compared to those without PCOS.
35 citations,
May 2022 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
1 citations,
December 2022 in “BMC Public Health” Long-term effects of COVID-19 can vary over time and are more likely in certain age and gender groups, while race, income, and education levels have little to no impact. Ongoing medical care is needed due to potential complications.
June 2022 in “Evidence-based complementary and alternative medicine” Acupressure improves quality of life in PCOS patients.
59 citations,
November 2010 in “Circulation Research” Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.
May 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” Testosterone significantly affects urination differences between male and female mice.
2 citations,
May 2019 in “PubMed” Oral finasteride and dutasteride may negatively affect erectile function in rats.
1 citations,
March 2024 in “Science” Vitamin A helps skin stem cells decide their function, aiding in hair growth and wound repair.
August 2024 in “Receptors” Vitamin D receptor is crucial for skin wound healing.
2 citations,
July 2021 in “Uro” Saw palmetto extract is generally safe and can effectively treat Lower Urinary Tract Symptoms, but its evaluation is affected by varying quality and a need for long-term studies.